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携带碳青霉烯酶基因新变体的临床分离株的全基因组序列

Complete genome sequence of a clinical isolate harboring a novel variant of the carbapenemase gene, .

作者信息

Kawase Jun, Kawakami Yuta, Fujisawa Naoki, Hayashi Hiroki, Nomura Ryoji, Kurahashi Masahiro, Wada Mieko, Suzuki Satowa

机构信息

Division of Bacteriology, Shimane Prefectural Institute of Public Health and Environmental Science, Matsue, Shimane, Japan.

Division of Atmospheric Environment, Shimane Prefectural Institute of Public Health and Environmental Science, Matsue, Shimane, Japan.

出版信息

Microbiol Resour Announc. 2025 Jul 10;14(7):e0019625. doi: 10.1128/mra.00196-25. Epub 2025 Jun 18.

DOI:10.1128/mra.00196-25
PMID:40530774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12243505/
Abstract

strain CRE21025 was isolated from a gallbladder abscess of a patient admitted to the hospital in Shimane Prefecture in 2021. Here, we present the complete genome sequence of this isolate, bearing a novel variant of the imipenemase-type gene, , by whole-genome sequencing using Oxford Nanopore and Illumina methods.

摘要

菌株CRE21025于2021年从岛根县一名住院患者的胆囊脓肿中分离得到。在此，我们通过使用牛津纳米孔和Illumina方法进行全基因组测序，展示了该分离株的完整基因组序列，其携带一种新型的亚胺培南酶型基因变体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db62/12243505/eec8fd9a45bf/mra.00196-25.f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db62/12243505/eec8fd9a45bf/mra.00196-25.f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db62/12243505/eec8fd9a45bf/mra.00196-25.f001.jpg

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本文引用的文献

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BMC Bioinformatics. 2025 Jan 7;26(1):3. doi: 10.1186/s12859-024-06030-y.
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Fast and robust metagenomic sequence comparison through sparse chaining with skani.通过使用 skani 进行稀疏链接实现快速稳健的宏基因组序列比较。
Nat Methods. 2023 Nov;20(11):1661-1665. doi: 10.1038/s41592-023-02018-3. Epub 2023 Sep 21.
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Emergence of rare carbapenemases (FRI, GES-5, IMI, SFC and SFH-1) in Enterobacterales isolated from surface waters in Japan.
在从日本地表水中分离出的肠杆菌科细菌中出现罕见碳青霉烯酶（FRI、GES-5、IMI、SFC和SFH-1）
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In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing.使用质粒查找工具（PlasmidFinder）和质粒多位点序列分型进行质粒的电子检测和分型
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