Abramovic Anto, Lener Sara, Hartmann Sebastian, Thomé Claudius
Department of Neurosurgery, Medical University of Innsbruck, Anichstrasse 35, Innsbruck, A-6020, Austria.
Acta Neurochir (Wien). 2025 Jun 18;167(1):171. doi: 10.1007/s00701-025-06590-9.
Lumbar spinal stenosis (LSS) is a common condition in the aging population, where decompressive surgery (DS) is widely regarded as the gold standard due to its effectiveness in relieving symptoms. However, DS carries the risk of secondary lumbar instability (SLI), while fusion surgery, although mitigating this risk, may lead to overtreatment and complications such as adjacent segment disease. The aim of the present study was to review the current literature on preoperative radiological and clinical variables, thus accounting for SLI after lumbar decompression surgery and to derive a score for SLI risk prediction.
A literature review using online databases was performed in order to identify risk factors for the emergence of SLI. Risk factors were then graded for relevance. Consequently, a risk score for predicting SLI was developed from these results.
25 studies including 9754 patients were identified. The most commonly described predictors for SLI were preoperative instability, disc height > 6.5 mm, surgical invasiveness as well as patient-related risk factors such as BMI, age, gender and presence of mechanical low back pain. Based on these results, a 14-point scale was created using the most relevant risk factors selected by the research group using a peer-review process.
The proposed score identifies known risk factors for SLI, rated according to their importance on clinical decision making. This represents an initial theoretical approach that has to be validated by prospective clinical studies. Nevertheless, decision making may already be supported by the awareness of the characterized risk factors.
腰椎管狭窄症(LSS)是老年人群中的常见病症,减压手术(DS)因其在缓解症状方面的有效性而被广泛视为金标准。然而,DS存在继发性腰椎不稳(SLI)的风险,而融合手术虽然可降低此风险,但可能导致过度治疗以及诸如相邻节段疾病等并发症。本研究的目的是回顾当前关于术前放射学和临床变量的文献,从而分析腰椎减压手术后发生SLI的情况,并得出SLI风险预测评分。
通过在线数据库进行文献综述,以确定SLI发生的风险因素。然后对风险因素的相关性进行分级。随后,根据这些结果制定了预测SLI的风险评分。
共纳入25项研究,涉及9754例患者。最常描述的SLI预测因素包括术前不稳、椎间盘高度>6.5mm、手术侵袭性以及患者相关风险因素,如体重指数、年龄、性别和存在机械性下腰痛。基于这些结果,研究小组通过同行评审过程选择最相关的风险因素,创建了一个14分制量表。
所提出的评分识别出了已知的SLI风险因素,并根据其对临床决策的重要性进行了评级。这是一种初步的理论方法,必须通过前瞻性临床研究进行验证。尽管如此,对这些特征性风险因素的认识可能已经有助于临床决策。