Zhao Chang, Rastogi Ritika, Woolverton G Alice, Yip Tiffany, Hahm Hyeouk Chris, Liu Cindy H
Department of Pediatrics, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Department of Pediatrics, Brigham and Women's Hospital, Boston, MA, USA.
J Affect Disord. 2025 Jun 16;389:119694. doi: 10.1016/j.jad.2025.119694.
Young adults experienced significant mental health challenges during the onset of the COVID-19 pandemic, yet the long-term trajectories of their mental health remain unclear. This longitudinal study examined anxiety and depression symptom trajectories among U.S. young adults from April-June 2020 to April-June 2022, identifying patterns of recovery, demographic disparities, and symptom fluctuation.
Data were drawn from the COVID-19 Adult Resilience Experiences Study (CARES), which followed 1221 U.S. young adults (ages 18-30; 83 % women) across four waves via online surveys. Mixed-effects growth models estimated trajectories of anxiety (GAD-7) and depression (PHQ-8) symptoms. Paired-samples t-tests tested mean differences between consecutive timepoints.
At baseline, anxiety (B = 9.59 (0.16), p < .001) and depression (B = 9.07 (0.16), p < .001) symptom levels approached the clinical cutoff (≥10). Significant decreases over time were observed for anxiety (B = -0.29 (0.03), p < .001) and depression symptoms (B = -0.20 (0.03), p < .001). However, symptom improvements were not uniform; for example, gender minorities showed persistently elevated depression symptoms. Anxiety and depression symptoms also fluctuated significantly across timepoints.
These findings challenged narratives of sustained mental health deterioration among young adults during the pandemic by demonstrating recovery. However, recovery varied by demographic groups. Symptom fluctuations underscored the need for flexible, responsive mental health care, particularly during periods of heightened societal stress.
在新冠疫情爆发期间,年轻人经历了重大的心理健康挑战,但其心理健康的长期轨迹仍不明朗。这项纵向研究调查了2020年4月至6月至2022年4月至6月期间美国年轻人的焦虑和抑郁症状轨迹,确定了恢复模式、人口统计学差异和症状波动情况。
数据来自新冠疫情成人复原力体验研究(CARES),该研究通过在线调查对1221名美国年轻人(18 - 30岁;83%为女性)进行了四轮跟踪。混合效应增长模型估计了焦虑(广泛性焦虑障碍量表 - 7,GAD - 7)和抑郁(患者健康问卷 - 8,PHQ - 8)症状的轨迹。配对样本t检验测试了连续时间点之间的平均差异。
在基线时,焦虑(B = 9.59(0.16),p <.001)和抑郁(B = 9.07(0.16),p <.001)症状水平接近临床临界值(≥10)。随着时间的推移,焦虑(B = -0.29(0.03),p <.001)和抑郁症状(B = -0.20(0.03),p <.001)显著下降。然而,症状改善并不均匀;例如,少数性别群体的抑郁症状持续升高。焦虑和抑郁症状在各时间点之间也有显著波动。
这些发现通过证明恢复情况,挑战了关于疫情期间年轻人心理健康持续恶化的说法。然而,恢复情况因人口统计学群体而异。症状波动凸显了灵活、响应性心理健康护理的必要性,特别是在社会压力加剧的时期。