Noah Kareem, Shaher Hussien, Hamdy Mariam, Diab Tamer, Farag Mahmoud
Urology Department, University Hospital Coventry and Warwickshire, Coventry, England.
Urology Department, Banha University, Banha, Egypt.
Int Urol Nephrol. 2025 Jun 19. doi: 10.1007/s11255-025-04605-z.
This study aimed to compare the predictive capabilities of three stone scoring systems (STONE, TOHO, and ITO stone score) in determining outcomes, stone-free status, and complications following flexible ureteroscopy (fURS) in patients with renal stones.
This prospective study included 300 patients with renal stones treated at the Urology Department of Benha University Hospital from January 2023 to June 2024, all managed with flexible ureteroscopy (fURS). Eligible participants had renal calculi measuring up to 2.5 cm. For each patient, the three evaluated stone scores were calculated by the same surgeon and an expert radiologist.
This study revealed significant negative correlations between stone-free rates (SFR) and the STONE and TOHO scores (P < 0.05), while there were significantly positive correlations between SFR and ITO scores (P value < 0.05). The SFR at 1 month was 87%. In terms of postoperative complications, colic was reported in 57 patients (19%), fever in 66 patients (22%), and hematuria in 30 patients (10%). According to the study findings, the three scoring systems effectively predicted the outcomes of flexible ureteroscopy, with area under the curve (AUC) values of 0.805 for STONE, 0.903 for TOHO, and 0.856 for ITOscore.
The three studied scoring systems are valid tools for predicting stone-free rates following flexible ureteroscopy in patients with renal stones. The significant correlations observed between these scores and the stone-free rates (87% at 1 month) highlight their effectiveness in assessing surgical outcomes.
本研究旨在比较三种结石评分系统(STONE、TOHO和ITO结石评分)在预测肾结石患者行输尿管软镜检查(fURS)后的治疗结果、结石清除状态及并发症方面的能力。
本前瞻性研究纳入了2023年1月至2024年6月在本哈大学医院泌尿外科接受治疗的300例肾结石患者,均采用输尿管软镜检查(fURS)进行治疗。符合条件的参与者的肾结石最大直径达2.5厘米。对于每位患者,由同一位外科医生和一名放射科专家计算三种评估结石评分。
本研究显示结石清除率(SFR)与STONE和TOHO评分之间存在显著负相关(P < 0.05),而SFR与ITO评分之间存在显著正相关(P值< 0.05)。1个月时的结石清除率为87%。在术后并发症方面,57例患者(19%)出现绞痛,66例患者(22%)发热,30例患者(10%)出现血尿。根据研究结果,这三种评分系统有效地预测了输尿管软镜检查的结果,STONE的曲线下面积(AUC)值为0.805,TOHO为0.903,ITO评分为0.856。
所研究的三种评分系统是预测肾结石患者输尿管软镜检查后结石清除率的有效工具。这些评分与结石清除率(1个月时为87%)之间观察到的显著相关性突出了它们在评估手术结果方面的有效性。