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机器人辅助微创食管癌切除术治疗食管癌患者:印度一家三级癌症护理中心的经验更新

Robot-assisted minimally invasive esophagectomy in patients with esophageal cancer: an update on experiences from a tertiary cancer care center in India.

作者信息

Nagarkar Raj, Jain Vikas, Kulkarni Nayana, Varadarajan Soundarya, Ramesh Yasam Venkata

机构信息

Department of Surgical Oncology, HCG Manavata Cancer Centre, Nashik, India.

Department of Anaesthesiology, HCG Manavata Cancer Centre, Nashik, India.

出版信息

J Minim Invasive Surg. 2025 Jun 15;28(2):74-80. doi: 10.7602/jmis.2025.28.2.74.

Abstract

PURPOSE

Robot-assisted minimally invasive esophagectomy (RAMIE) for esophageal cancers, has gained traction in the last decade due to its positive surgical outcomes. The present study is an update to our earlier published data, in which we discuss the new developments in terms of perioperative and postoperative outcomes of our patients.

METHODS

This is a single-center, retrospective data of patients who underwent RAMIE for esophageal cancers between January 2020 to October 2024 at a tertiary cancer center in India.

RESULTS

A total of 52 patients have undergone RAMIE at our center to date. The median age of the cohort was 56.02 ± 11.69 years, with a slight male predominance (n = 29, 55.77%). Majority of the patients were of American Society of Anesthesiologists physical status classification II (n = 40, 76.92%), Eastern Cooperative Oncology Group status 1 (n = 35, 67.30%), with no comorbidities (n = 36, 69.23%), and presented with stage 2 disease (n = 21, 40.37%). Squamous cell carcinoma was the predominant histological subtype (n = 31, 59.62%). The median operative time was 111.6 (range, 60-180) minutes with a median lymph node harvest of 12 (range, 7-24). The median intensive care unit stay was 2 (range, 2-5) days, and the median total hospital stay was 6 (range, 3-9) days. No major postoperative complications were observed. The 30-day mortality rate was reported in two patients (3.85%).

CONCLUSION

The results of our research indicate that RAMIE may serve as a safe and effective surgical option for esophageal cancers, leading to improved perioperative and postoperative outcomes.

摘要

目的

机器人辅助微创食管癌切除术(RAMIE)在过去十年中因其良好的手术效果而受到关注。本研究是对我们早期发表数据的更新,在此次更新中,我们讨论了患者围手术期和术后结果方面的新进展。

方法

这是一项单中心回顾性研究,数据来源于2020年1月至2024年10月在印度一家三级癌症中心接受RAMIE治疗的食管癌患者。

结果

截至目前,共有52例患者在我们中心接受了RAMIE手术。该队列患者的中位年龄为56.02±11.69岁,男性略占优势(n = 29,55.77%)。大多数患者美国麻醉医师协会身体状况分级为II级(n = 40,76.92%),东部肿瘤协作组状态为1级(n = 35,67.30%),无合并症(n = 36,69.23%),且为2期疾病(n = 21,40.37%)。鳞状细胞癌是主要的组织学亚型(n = 31,59.62%)。中位手术时间为111.6(范围60 - 180)分钟,中位淋巴结清扫数为12(范围7 - 24)。中位重症监护病房停留时间为2(范围2 - 5)天,中位总住院时间为6(范围3 - 9)天。未观察到重大术后并发症。报告的30天死亡率为2例患者(3.85%)。

结论

我们的研究结果表明,RAMIE可能是一种安全有效的食管癌手术选择,可改善围手术期和术后结果。

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本文引用的文献

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Robot-assisted minimally invasive esophagectomy (RAMIE) improves perioperative outcomes: a review.
J Thorac Dis. 2019 Apr;11(Suppl 5):S735-S742. doi: 10.21037/jtd.2018.11.104.
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Extent of Lymphadenectomy Is Associated With Improved Overall Survival After Esophagectomy With or Without Induction Therapy.
Ann Thorac Surg. 2017 Feb;103(2):406-415. doi: 10.1016/j.athoracsur.2016.08.010. Epub 2016 Dec 23.

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