Forged Without FIRE: Normal Brain Development in the Absence of Microglia.
作者信息
Varvel Nicholas H
机构信息
Department of Pharmacology and Chemical Biology, Emory School of Medicine, Atlanta, GA, USA.
出版信息
Epilepsy Curr. 2025 Jun 16:15357597251348961. doi: 10.1177/15357597251348961.
Abstract
摘要
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本文引用的文献
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Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus.在皮质和丘脑，典型的突触和神经元特性的发育可以在没有小胶质细胞的情况下进行。
Nat Neurosci. 2025 Feb;28(2):268-279. doi: 10.1038/s41593-024-01833-x. Epub 2025 Jan 6.
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The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity.小胶质细胞先天免疫受体 TREM2 对于突触消除和正常大脑连接是必需的。
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