Fellows I W, Macdonald I A, Bennett T, Allison S P
Clin Sci (Lond). 1985 Nov;69(5):525-32. doi: 10.1042/cs0690525.
With use of a liquid-conditioned coverall, the thermoregulatory responses to a lowering of environmental temperature from 35 degrees C to 23 degrees C were assessed in eight normally nourished and six undernourished elderly female patients, during their convalescence after surgical repair of a fracture of the femoral neck. There was no difference in the peripheral vasoconstriction of the two groups in response to a cold environment. On lowering the environmental temperature, the increase in metabolic rate was significantly impaired in the undernourished group compared with the normally nourished group (P less than 0.05). There was a small decrease in core temperature in the undernourished group (median change -0.1 degree C) during the period of exposure to the lowest environmental temperature (23 degrees C). This was significantly different from the lack of change (median change 0 degrees C) in core temperature observed in the normally nourished group (P less than 0.05). This defect of thermogenesis may underlie the propensity of undernourished elderly patients to suffer hypothermia and fracture of the femoral neck in the winter months.
使用液体调节工作服，对8名营养正常和6名营养不良的老年女性患者在股骨颈骨折手术修复后的恢复期进行评估，观察她们在环境温度从35摄氏度降至23摄氏度时的体温调节反应。两组在寒冷环境下的外周血管收缩情况没有差异。在降低环境温度时，与营养正常组相比，营养不良组的代谢率增加明显受损（P<0.05）。在暴露于最低环境温度（23摄氏度）期间，营养不良组的核心体温略有下降（中位数变化-0.1摄氏度）。这与营养正常组观察到的核心体温无变化（中位数变化0摄氏度）有显著差异（P<0.05）。这种产热缺陷可能是营养不良的老年患者在冬季易患体温过低和股骨颈骨折的原因。
