Zhang Zizhong, Sun Guangkun, Ye Jiacheng, Liu Bin, Wang Yongzheng, Li Yuliang, Chang Haiyang
Department of General Surgery, Wucheng People's Hospital, Dezhou, China.
Imaging Department, Liaocheng Traditional Chinese Medicine Hospital, Liaocheng, China.
Front Cardiovasc Med. 2025 Jun 4;12:1566798. doi: 10.3389/fcvm.2025.1566798. eCollection 2025.
Castor-branched stent-graft, chimney stent, and fenestration techniques have been employed for left subclavian artery (LSA) revascularization during zone 2 thoracic endovascular aortic repair (TEVAR), but not recommended routinely. This study aimed to compare the safety and efficacy of these techniques.
From February 2017 to June 2020, 133 patients with type B acute aortic syndromes undergoing LSA revascularization during zone 2 TEVAR were retrospectively enrolled. The primary outcomes include technical success, mortality, stroke and spinal cord ischemia. The secondary outcomes include aortic remodeling, LSA patency, freedom from aorta-related reintervention.
Fifty patients were treated with the Castor-branched stent-graft (Group A), 42 with the chimney technique (Group B), and 41 with the fenestration technique (Group C). The groups demonstrated a similar technical success rate, with 96% in Group A, 97.62% in Group B, and 95.12% in Group C. Despite a more predominant bird-beak configuration in group A ( = 0.003), no significant difference was observed in perioperative complications. Two TEVAR-related deaths occurred in Groups B and C, while none was reported in Group A. During the first two years of follow-up, favorable aortic remodeling was confirmed in all groups. Each group exhibited two cases of LSA occlusions. Aorta-related reintervention and mortality did not significantly differ among the groups.
Endovascular techniques are feasible for LSA revascularization during zone 2 TEVAR, with favorable aortic remodeling. However, the durability of these procedures requires careful evaluation, given the potential concern of LSA occlusion.
在2区胸主动脉腔内修复术(TEVAR)期间,已采用分支型支架移植物、烟囱式支架和开窗技术进行左锁骨下动脉(LSA)血运重建,但不常规推荐使用。本研究旨在比较这些技术的安全性和有效性。
回顾性纳入2017年2月至2020年6月期间133例在2区TEVAR期间接受LSA血运重建的B型急性主动脉综合征患者。主要结局包括技术成功、死亡率、卒中及脊髓缺血。次要结局包括主动脉重塑、LSA通畅、无需主动脉相关再次干预。
50例患者接受分支型支架移植物治疗(A组),42例采用烟囱技术(B组),41例采用开窗技术(C组)。各组技术成功率相似,A组为96%,B组为97.62%,C组为95.12%。尽管A组的鸟嘴样形态更为明显(P = 0.003),但围手术期并发症无显著差异。B组和C组发生2例与TEVAR相关的死亡,而A组未报告死亡病例。在随访的前两年,所有组均证实主动脉重塑良好。每组均出现2例LSA闭塞病例。各组间主动脉相关再次干预和死亡率无显著差异。
血管内技术在2区TEVAR期间进行LSA血运重建是可行的,主动脉重塑良好。然而,鉴于LSA闭塞的潜在问题,这些手术的耐久性需要仔细评估。