Fischbach Anna, Simons Julia Alexandra, Wiegand Steffen Bernhard, Lang Celiné, Kopp Rüdger, Marx Gernot, Bauer Sebastian Johannes, Winnersbach Patrick, Akhyari Payam, Schälte Gereon
Department of Anesthesiology, RWTH Aachen University, Aachen, 52074 Germany.
Department of Anesthesia and Intensive Care Medicine, Hannover Medical School, Hannover, 30625 Germany.
Indian J Thorac Cardiovasc Surg. 2025 Jul;41(7):863-873. doi: 10.1007/s12055-025-01908-9. Epub 2025 Mar 24.
Coronary artery bypass graft (CABG) surgery is the standard treatment for advanced coronary artery disease. Despite evidence supporting enhanced recovery after surgery (ERAS) programs, many hospitals continue to keep patients intubated following on-pump CABG surgery. The coronavirus disease 2019 (COVID-19) pandemic further strained intensive care unit (ICU) capacities, leading to the consideration of immediate extubation after elective surgeries like CABG surgeries. The aim of this study was to assess whether extubation in the operating room after elective on-pump CABG surgery would reduce the ICU length of stay, the ICU readmission, and the ICU mortality in a population of patients undergoing on-pump CABG surgery as opposed to the conventional approach with patients remaining intubated.
This study is a retrospective single-center study, including data from the University Hospital Aachen, Germany. Clinical data from 2019 to 2022 were analyzed, focusing on patients who underwent on-pump CABG surgery. Primary endpoints studied were the duration of ICU stay, rates of ICU readmission, and ICU mortality. Secondary outcomes included the hospital length of stay, hospital mortality, and the occurrence of postoperative pneumonia.
Ninety-seven patients who underwent elective on-pump CABG surgery were identified. There were no variations in outcomes, including ICU and hospital stays, mortality, ICU readmission, or postoperative pneumonia between the two groups.
Extubation in the operating room after on-pump CABG surgery did not result in significant differences in outcomes compared to patients who remained intubated.
The online version contains supplementary material available at 10.1007/s12055-025-01908-9.
冠状动脉旁路移植术(CABG)是晚期冠状动脉疾病的标准治疗方法。尽管有证据支持术后加速康复(ERAS)方案,但许多医院在体外循环CABG手术后仍继续让患者插管。2019冠状病毒病(COVID-19)大流行进一步加剧了重症监护病房(ICU)的压力,促使人们考虑在CABG手术等择期手术后立即拔管。本研究的目的是评估择期体外循环CABG手术后在手术室拔管与患者保持插管的传统方法相比,是否会减少接受体外循环CABG手术患者的ICU住院时间、ICU再入院率和ICU死亡率。
本研究是一项回顾性单中心研究,包括来自德国亚琛大学医院的数据。分析了2019年至2022年的临床数据,重点关注接受体外循环CABG手术的患者。研究的主要终点是ICU住院时间、ICU再入院率和ICU死亡率。次要结局包括住院时间、医院死亡率和术后肺炎的发生情况。
确定了97例接受择期体外循环CABG手术的患者。两组之间在结局方面没有差异,包括ICU和住院时间、死亡率、ICU再入院率或术后肺炎。
与仍保持插管的患者相比,体外循环CABG手术后在手术室拔管并未导致结局出现显著差异。
在线版本包含可在10.1007/s12055-025-01908-9获取的补充材料。