Dheyauldeen Sinan, Heimdal Ketil, Osnes Terje, Akre Harriet, Olsson Lars
Department of Otorhinolaryngology, Head and Neck Surgery Oslo University Hospital-Rikshospitalet Oslo Norway.
The Medical Faculty University of Oslo Oslo Norway.
World J Otorhinolaryngol Head Neck Surg. 2024 Jun 30;11(2):207-212. doi: 10.1002/wjo2.196. eCollection 2025 Jun.
Choanal atresia (CA) is a congenital narrowing or obliteration of the posterior nasal aperture. The condition is rare with an incidence of approximately 1 in 5000 to 9000 live births.
The aim of this work was to assess the results of treating this condition at the Otolaryngology Department in Oslo University Hospital-Rikshospitalet.
Retrospective review of patients treated at Oslo University Hospital-Rikshospitalet between 2005 and 2015 were performed. The review consisted of surgical techniques and outcomes, types of atresia, uses of stent and mitomycin C, age at operation, laterality of atresia, and associated anomalies.
Thirty-one patients with CA were referred to Oslo University Hospital-Rikshospitalet during the mentioned observation period. Nine (29%) of the cases had bilateral CA and 22 (71%) had unilateral CA. Ten patients (32%) had bony atresia, 12 (39%) had membranous and eight (26%) had mixed type of atresia. Twenty-one patients (68%) needed revision surgery because of complete or partial restenosis after primary surgery. Stents were applied in 16 cases (52%) of patients and Mitomycin C was only used in the primary surgery of three patients. In the bilateral group, eight of the nine patients were operated on within the first 9 days of life. Sixteen patients (45%) had associated anomalies.
According to the observations in our sample, the restenosis problem is expected more and may need more revisions in bilateral CA than the unilateral type. The presence of other anomalies is associated with higher incidence of restenosis. Stenting is not essential in preventing restenosis.
后鼻孔闭锁(CA)是后鼻孔的先天性狭窄或闭塞。这种情况很罕见,在活产婴儿中的发病率约为1/5000至1/9000。
这项工作的目的是评估奥斯陆大学医院-里克斯胡斯医院耳鼻喉科治疗这种疾病的结果。
对2005年至2015年在奥斯陆大学医院-里克斯胡斯医院接受治疗的患者进行回顾性研究。该研究包括手术技术和结果、闭锁类型、支架和丝裂霉素C的使用、手术年龄、闭锁的侧别以及相关畸形。
在上述观察期内,31例CA患者被转诊至奥斯陆大学医院-里克斯胡斯医院。其中9例(29%)为双侧CA,22例(71%)为单侧CA。10例患者(32%)为骨性闭锁,12例(39%)为膜性闭锁,8例(26%)为混合型闭锁。21例患者(68%)因初次手术后完全或部分再狭窄而需要再次手术。16例(52%)患者使用了支架,丝裂霉素C仅在3例患者的初次手术中使用。在双侧组中,9例患者中有8例在出生后的前9天内接受了手术。16例患者(45%)伴有相关畸形。
根据我们样本中的观察结果,预计双侧CA比单侧CA的再狭窄问题更多,可能需要更多次的再次手术。其他畸形的存在与再狭窄的较高发生率相关。支架置入对于预防再狭窄并非必不可少。