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口腔无创神经电刺激治疗阻塞性睡眠呼吸暂停的效果:一项系统评价。

Effect of non-invasive neuroelectric stimulation of oral cavity for obstructive sleep apnoea: A systematic review.

作者信息

Awan Muhammad Ozair, Arif Aahan, Adeel Mohammad, Ahmed Shahzada, Iftikhar Haissan

机构信息

Medical College Aga Khan University Hospital Karachi Pakistan.

Department of Otolaryngology Bradford Teaching Hospital Bradford UK.

出版信息

World J Otorhinolaryngol Head Neck Surg. 2024 Nov 5;11(2):290-297. doi: 10.1002/wjo2.220. eCollection 2025 Jun.

Abstract

OBJECTIVES

With an estimated disease burden of one billion adults aged 30-69, obstructive sleep apnea (OSA) offers considerable challenges in terms of both identification and management Neuroelectric stimulation offers benefit with studies showing improvement in both the respiratory disturbance index and apnoea-hypopnoea index. This systematic review aims to examine the effects of non-invasive neuroelectric stimulation of the oral cavity utilized in the treatment of OSA.

METHODS

A systematic search of PubMed, EBSCO CINAHL Plus, EBSCO Dentistry and Oral Sciences Source and Wiley Cochrane Library was utilized to identify articles. A total of 4 articles investigating 154 participants were included in the final synthesis. Data was extracted to by two authors (MOA and HI) working independently of each other. Any discrepancies that arose were discussed and resolved.

RESULTS

Our results demonstrated that non-invasive neurostimulation serves as an avenue for management that can allow for improvements in functionality as well as oxygen saturation amongst patients suffering from mild to moderate OSA.

CONCLUSION

Due to the dearth of research, it is imperative that further studies are done to investigate the efficacy of neuromuscular stimulation, as these findings cannot be generalized across different populations.

摘要

目的

阻塞性睡眠呼吸暂停(OSA)估计给10亿30至69岁成年人带来疾病负担,在识别和管理方面都带来了巨大挑战。神经电刺激显示出益处,研究表明呼吸紊乱指数和呼吸暂停低通气指数均有所改善。本系统评价旨在研究口腔非侵入性神经电刺激治疗OSA的效果。

方法

系统检索了PubMed、EBSCO CINAHL Plus、EBSCO牙科学与口腔科学资源库以及Wiley Cochrane图书馆以识别文章。最终纳入了4篇研究154名参与者的文章进行综合分析。数据由两位作者(MOA和HI)独立提取。出现的任何差异都进行了讨论并解决。

结果

我们的结果表明,非侵入性神经刺激是一种治疗途径,可使轻至中度OSA患者的功能和血氧饱和度得到改善。

结论

由于研究不足,必须进一步开展研究以调查神经肌肉刺激的疗效,因为这些结果不能推广到不同人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0540/12172099/4d44fc4e108e/WJO2-11-290-g001.jpg

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