Eissa M K, Sparks R A, Newton J R
Contraception. 1985 Jul;32(1):87-95. doi: 10.1016/0010-7824(85)90118-0.
Immunoglobulin levels were measured by agar gel single radial immunodiffusion in the serum and cervical mucus of 50 tailed copper IUD users, 20 combined oral contraceptive users and 20 women not using contraception (controls). IgG, IgA and IgM levels were significantly higher in the copper IUD users compared to the other two groups. It is not known whether this was related to the small numbers of bacteria found in the uterine cavity of tailed IUD users or to the foreign body reaction of the device.
采用琼脂凝胶单向放射免疫扩散法测定了50名使用带铜宫内节育器（IUD）的妇女、20名使用复方口服避孕药的妇女和20名未使用避孕措施的妇女（对照组）血清和宫颈黏液中的免疫球蛋白水平。与其他两组相比，使用铜IUD的妇女的IgG、IgA和IgM水平显著更高。尚不清楚这是与在使用带尾IUD的妇女子宫腔中发现的少量细菌有关，还是与该装置的异物反应有关。
