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跨物种的白内障-晶状体混浊比较

Comparative cataract-lens opacification across species.

作者信息

Williams David

机构信息

Queen's Veterinary School Hospital, Department of Veterinary Medicine, University of Cambridge, Madingley Rd, Cambridge, CB3 0ES, UK.

出版信息

Eye (Lond). 2025 Jun 19. doi: 10.1038/s41433-025-03874-3.

Abstract

Around 12 million people globally are estimated to be blind with age-related cataract and numerous studies have sought to evaluate the causes of this lens opacification, many of these complicated by the difficulty of determining the impacts of varying aetiological factors from daylight through diet, diabetes and many more. While various experimental investigations on laboratory animals have sought to unpick these influences on lens transparency to date none has sought to evaluate age-related cataract across different animal species kept as companion animals. Here we look at a number of studies on companion dogs, cats and horses to determine the effects of daylight, diet, diabetes, dehydration, drugs, genetics (DNA to continue the D alliteration) and trauma (Damage again as a final D).

摘要

据估计,全球约有1200万人因年龄相关性白内障而失明,许多研究试图评估这种晶状体混浊的原因,其中许多研究因难以确定从日光到饮食、糖尿病等各种病因因素的影响而变得复杂。虽然迄今为止对实验动物进行的各种实验研究试图剖析这些对晶状体透明度的影响,但没有一项研究试图评估作为伴侣动物饲养的不同动物物种的年龄相关性白内障。在这里,我们研究了一些关于伴侣犬、猫和马的研究,以确定日光、饮食、糖尿病、脱水、药物、遗传学(DNA,继续以D开头)和创伤(再次以D开头的Damage)的影响。

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