Wang Qixuan, Ma Chen, Zhang Ling
Laser Aesthetic Center, Plastic Surgery Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, No. 33, Badachu Road, Shijingshan District, Beijing, China.
Aesthetic Plast Surg. 2025 Jun 19. doi: 10.1007/s00266-025-05023-3.
This scoping review comprehensively evaluates the role of radiofrequency microneedling (RFM) in facial rejuvenation, focusing on its applications across specific anatomical regions, integration with transdermal drug delivery and outcome assessments. Searching on PubMed, Web of Science and Embase indicates that RFM is multifunctional in the treatment of cheeks, periorbital regions, mandible, lower face, neck and photoaging. The combination of RFM with agents like poly-L-lactic acid, polynucleotides, platelet-rich plasma and trichloroacetic acid further enhances treatment outcomes, promoting collagen synthesis and skin repair. The outcome assessment used to assess the efficacy and safety of RFM treatment were concluded, which were categorized into subjective (patient satisfaction) and objective (clinical evaluations) measures, provide a comprehensive understanding of efficacy and guide personalized treatment strategies. This review highlights RFM's significant potential as a versatile and effective tool in facial rejuvenation.Level of Evidence I This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
本综述全面评估了射频微针（RFM）在面部年轻化中的作用，重点关注其在特定解剖区域的应用、与透皮给药的结合以及疗效评估。在PubMed、科学网和Embase上进行检索表明，RFM在治疗脸颊、眶周区域、下颌、下脸、颈部和光老化方面具有多种功能。RFM与聚左旋乳酸、多核苷酸、富血小板血浆和三氯乙酸等药物联合使用可进一步提高治疗效果，促进胶原蛋白合成和皮肤修复。总结了用于评估RFM治疗疗效和安全性的疗效评估，这些评估分为主观（患者满意度）和客观（临床评估）指标，有助于全面了解疗效并指导个性化治疗策略。本综述强调了RFM作为面部年轻化中一种多功能且有效的工具的巨大潜力。证据级别I 本刊要求作者为每篇文章指定证据级别。有关这些循证医学评级的完整描述，请参阅目录或作者在线指南 www.springer.com/00266 。
