Mahapatra Smruti, Bhimarasetty Vishal N, Rahim Abdul, Curtis Colin N, Gulotta Paul, Sarkar Korak
Department of Neurosurgery, Tulane University School of Medicine, New Orleans, LA.
Neurosciences BioDesign Lab, Ochsner Clinic Foundation, New Orleans, LA.
Ochsner J. 2025 Summer;25(2):92-98. doi: 10.31486/toj.24.0124.
Cerebrovascular disease is a leading cause of death and disability worldwide, and endovascular therapies have become a mainstay of treatment for ischemic stroke. However, tortuous anatomy, particularly of the aortic arch, presents formidable treatment challenges by impeding access to intracranial circulation and thus affecting clinical outcomes.
To better understand the challenges of tortuous anatomy, we fabricated 3D-printed models of the aortic arch and major branch vessels based on the imaging of 4 patients.
These patient-specific models were realistic representations of the intricate vascular pathways and provided enhanced visualization of the complex vascular structures. The measured diameters of the 3D-fabricated models closely matched the values reported in the literature, confirming the physical accuracy of the models. Creating an individual anatomic model required an average of 4 hours of digital processing and 13.71 hours of 3D printing, with a materials cost of approximately $17.31.
3D-printed patient-specific models used for neurointerventional training and preprocedural planning are a valuable tool for managing complex cerebrovascular anatomy. The advanced visualization provided by these models may enhance preparedness and potentially improve ischemic stroke treatment outcomes.
脑血管疾病是全球死亡和残疾的主要原因，血管内治疗已成为缺血性卒中治疗的主要手段。然而，特别是主动脉弓的迂曲解剖结构，通过阻碍进入颅内循环从而影响临床结果，带来了巨大的治疗挑战。
为了更好地理解迂曲解剖结构的挑战，我们基于4例患者的成像制作了主动脉弓和主要分支血管的3D打印模型。
这些针对患者的模型逼真地呈现了复杂的血管路径，并增强了对复杂血管结构的可视化。3D制作模型的测量直径与文献报道的值密切匹配，证实了模型的物理准确性。创建一个个体解剖模型平均需要4小时的数字处理和13.71小时的3D打印，材料成本约为17.31美元。
用于神经介入训练和术前规划的3D打印患者特异性模型是管理复杂脑血管解剖结构的宝贵工具。这些模型提供的先进可视化可能会增强准备工作，并有可能改善缺血性卒中的治疗结果。
