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神经白塞病:一例报告

Neuro-Behçet's Syndrome: A Case Report.

作者信息

LeRoy David I, Ognjanovski Elaine, Menkes Silvia, Kenny Kristen, Konja Cassie

机构信息

Internal Medicine, Henry Ford Health System - Warren, Warren, USA.

Neurology, Henry Ford Health System - Warren, Warren, USA.

出版信息

Cureus. 2025 May 19;17(5):e84421. doi: 10.7759/cureus.84421. eCollection 2025 May.

Abstract

Behçet's syndrome is a systemic vasculitis characterized by recurrent oral and genital ulcers, uveitis, and often involvement of multiple organ systems. Neurological involvement is a rare complication of Behçet's syndrome and is associated with significant morbidity and mortality. Neuro-Behçet's syndrome (NBS) is a combination of neurologic manifestations in a patient with Behçet's syndrome, including movement disorders, myelopathic syndrome, intracranial hypertension, and a multiple sclerosis-like presentation. Diagnosis of NBS can be challenging due to the wide range of clinical presentations. Although previous research has aided in advancing the understanding of the pathophysiology and treatment of systemic Behçet's syndrome, there is a lack of randomized controlled studies involving the treatment of NBS. This case report describes a patient with NBS who experienced a complex hospital course, highlighting the need for a multidisciplinary team approach to address various complications.

摘要

白塞病是一种全身性血管炎,其特征为复发性口腔溃疡和生殖器溃疡、葡萄膜炎,且常累及多个器官系统。神经系统受累是白塞病的一种罕见并发症,与显著的发病率和死亡率相关。神经白塞病(NBS)是白塞病患者出现的神经学表现的组合,包括运动障碍、脊髓病综合征、颅内高压以及类似多发性硬化的表现。由于临床表现范围广泛,NBS的诊断可能具有挑战性。尽管先前的研究有助于增进对全身性白塞病病理生理学和治疗的理解,但缺乏涉及NBS治疗的随机对照研究。本病例报告描述了一名经历复杂住院过程的NBS患者,强调了采用多学科团队方法来应对各种并发症的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/235d/12177433/e1a94f2e68ad/cureus-0017-00000084421-i01.jpg

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