Kushwaha Swapnil S, Goyal Abhilash, Goja Shikha
Urology, Max Super Speciality Hospital, Saket, Delhi, IND.
General Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, Delhi, IND.
Cureus. 2025 May 19;17(5):e84435. doi: 10.7759/cureus.84435. eCollection 2025 May.
Extra-gastrointestinal stromal tumors (eGISTs) are rare tumors that occur outside the gastrointestinal tract but share similar histological and molecular characteristics as GISTs. This report highlights an exceptionally rare case of eGISTs in the urinary bladder of a 40-year-old man who presented with painless gross total hematuria. Computed tomography (CT) revealed a solitary bladder mass, approximately 3 × 3 cm over the anterior wall, with extravesical extension into the urachal remnants. He was diagnosed with eGIST of the urinary bladder based on histopathology and immunohistochemistry after cystoscopy and transurethral resection. The patient underwent open partial cystectomy and excision of the urachus, with an uneventful recovery and no recurrence at 28 months follow-up. This case report underscores the importance of recognizing and appropriately managing bladder eGISTs.
胃肠道外间质瘤（eGISTs）是一种罕见肿瘤，发生于胃肠道外，但具有与胃肠道间质瘤（GISTs）相似的组织学和分子特征。本报告重点介绍了一例极其罕见的eGISTs病例，患者为一名40岁男性，表现为无痛性肉眼全程血尿，计算机断层扫描（CT）显示膀胱前壁有一个孤立的膀胱肿块，大小约为3×3cm，肿块向膀胱外延伸至脐尿管残余部分。经膀胱镜检查和经尿道切除术后，根据组织病理学和免疫组化结果，该患者被诊断为膀胱eGISTs。患者接受了开放性部分膀胱切除术和脐尿管切除术，术后恢复顺利，随访28个月无复发。本病例报告强调了认识和妥善处理膀胱eGISTs的重要性。
