Morrey B F, Fitzgerald R H, Kelly P J, Dobyns J H, Washington J A
J Bone Joint Surg Am. 1977 Jun;59(4):527-30.
Isolates of either Corynebacterium diphtheriae or Propionibacterium acnes from osteomyelitis are not necessarily contaminants, as shown by the cases of three patients who had bone and joint infections in which these organisms were pathogenic (one in pure culture and two in mixed cultures). Previous operation or other factors that compromise host resistance create the setting for these opportunistic organisms. Penicillin with or without streptomycin is the treatment of choice, but if penicillin or streptomycin cannot be used then the cephalosporins, clindamycin, and erythromycin are acceptable alternatives (depending on susceptibility studies). In general, the prognosis is good.
从骨髓炎中分离出的白喉棒状杆菌或痤疮丙酸杆菌不一定是污染物，三名患有骨和关节感染的患者的病例表明，这些微生物具有致病性（一例为纯培养，两例为混合培养）。先前的手术或其他损害宿主抵抗力的因素为这些机会性微生物创造了条件。青霉素加或不加链霉素是首选治疗方法，但如果不能使用青霉素或链霉素，那么头孢菌素、克林霉素和红霉素是可接受的替代药物（取决于药敏试验）。一般来说，预后良好。
