Theofilis Panagiotis, Nakas Nikolaos, Lamprou Thomais, Touchantzidou Kalliopi, Vordoni Aikaterini, Thimis Vasilios, Smirloglou Despina, Kotsakis Athanasios, Kalaitzidis Rigas G
Center for Nephrology "G. Papadakis", General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Ioannina, Greece.
2nd Cardiology Department, General Hospital of Nikaia-Piraeus "Ag. Panteleimon", Nikaia, Greece.
J Hum Hypertens. 2025 Jun 20. doi: 10.1038/s41371-025-01033-5.
Hypertensive urgencies (HU) and hypertensive emergencies (HE) are common conditions in the cardiology emergency department (ED), often requiring urgent intervention. Despite their clinical significance, data on patient characteristics, etiologies, and management strategies remain limited. This study aimed to assess the epidemiology, clinical profile, and management of HU and HE in a tertiary cardiology ED. A single-center, observational study was conducted over 12 months, enrolling patients diagnosed with HU/HE (BP ≥ 180/120 mmHg). Demographic data, medical history, symptoms, etiologic factors, and antihypertensive treatments were recorded. Serial blood pressure (BP) measurements were taken to assess BP reduction during the ED stay. Of 4010 cardiology ED visits, 83 patients (2.1%) had HU/HE (median age 65 years, 45.8% male). Most had a history of hypertension (73.5%), with frequent coexisting smoking (56.6%) and dyslipidemia (43.4%). Common symptoms included dyspnea (19.3%) and chest pain (25.3%). Stress (26.8%) and increased salt intake (15.9%) were common etiologic factors. HE was diagnosed in 18 cases (21.7%), and 12.7% of HU cases required hospitalization. Mean BP on admission was 200/100 mmHg, with SBP and DBP reductions of 41 mmHg (-21%) and 18 mmHg (-17%), respectively. Nitrates, anxiolytics, and combination therapies resulted in the greatest BP reductions. In conclusion, HU and HE are frequently observed in hypertensive patients with additional cardiovascular risk factors. Target-organ damage is not solely related to BP levels, emphasizing the need for individualized management strategies.
高血压急症(HU)和高血压亚急症(HE)是心脏病急诊科(ED)的常见病症,常需紧急干预。尽管它们具有临床重要性,但关于患者特征、病因及管理策略的数据仍然有限。本研究旨在评估三级心脏病急诊科中HU和HE的流行病学、临床特征及管理情况。进行了一项为期12个月的单中心观察性研究,纳入诊断为HU/HE(血压≥180/120 mmHg)的患者。记录人口统计学数据、病史、症状、病因及降压治疗情况。进行连续血压(BP)测量以评估急诊留观期间的血压下降情况。在4010次心脏病急诊科就诊中,83例患者(2.1%)患有HU/HE(中位年龄65岁,男性占45.8%)。大多数患者有高血压病史(73.5%),常并存吸烟(56.6%)和血脂异常(43.4%)。常见症状包括呼吸困难(19.3%)和胸痛(25.3%)。应激(26.8%)和盐摄入量增加(15.9%)是常见病因。18例(21.7%)诊断为HE,12.7%的HU患者需要住院治疗。入院时平均血压为200/100 mmHg,收缩压和舒张压分别下降41 mmHg(-21%)和18 mmHg(-17%)。硝酸盐、抗焦虑药及联合治疗导致最大程度的血压下降。总之,在伴有其他心血管危险因素的高血压患者中,HU和HE较为常见。靶器官损害并非仅与血压水平相关,这强调了个体化管理策略的必要性。