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新生雏鸡肝脏和肠微粒体脂质成分的发育:胆固醇喂养引起的变化。

Development of lipidic composition of neonatal chick liver and intestine microsomes: changes induced by cholesterol feeding.

作者信息

Alejandre M J, Zafra M F, Ramirez H, Segovia J L, Garcia-Peregrin E

出版信息

Int J Biochem. 1985;17(7):835-8. doi: 10.1016/0020-711x(85)90273-3.

Abstract

Changes in cholesterol and phospholipid content of chick liver and intestine microsomes were studied throughout the two first weeks of life. Differences observed throughout postnatal development were mainly due to the free cholesterol. Cholesterol feeding resulted in a clear increase of the amounts of both free and esterified cholesterol. Phospholipid content of chick liver and intestine microsomes did not change significantly after hatching. Phosphatidylcholine and phosphatidylethanolamine were found to be the major phospholipids. Although the amount of each phospholipid could be affected by cholesterol feeding, its relative percentage did not change by this treatment.

摘要

在雏鸡出生后的头两周内,对其肝脏和肠道微粒体中的胆固醇和磷脂含量变化进行了研究。在出生后的发育过程中观察到的差异主要归因于游离胆固醇。喂食胆固醇导致游离胆固醇和酯化胆固醇的含量明显增加。雏鸡肝脏和肠道微粒体的磷脂含量在孵化后没有显著变化。发现磷脂酰胆碱和磷脂酰乙醇胺是主要的磷脂。尽管每种磷脂的含量可能会受到胆固醇喂食的影响,但其相对百分比不受该处理的影响。

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