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[生物瓣和机械瓣人工瓣膜病理学诊断。I. 临床和超声心动图评估]

[The diagnosis of prosthesis pathology in biological and mechanical valves. I. Clinical and echocardiographic evaluation].

作者信息

Dander B, Tovena D, Buonanno C, Rossi R, Righetti B, Marino P, Zardini P

出版信息

G Ital Cardiol. 1985 May;15(5):478-84.

PMID:4054483
Abstract

We retrospectively evaluated the clinical and echocardiographic findings of 50 patients with documented malfunctioning of cardiac prosthetic valves. The prostheses, mechanical or biological, were in 24 cases in a mitral and in 26 cases in an aortic position. Prosthetic dysfunction was due to thrombosis, fibro-calcific degeneration, fibrous cloth, bacterial infection, dehiscence, mismatch. The clinical features were represented by cardiac insufficiency of different degrees, up to global congestive failure unresponsive to medical treatment, by sudden low-output syndrome, arrhythmias, angina. The changes in auscultatory findings have appeared important clues to prosthetic malfunction, but we stress the necessity of an instrumental documentation of the type and grade of dysfunction. Echocardiography has represented an essential tool for a rapid and accurate noninvasive diagnosis of prosthetic pathology. The echocardiographic examination, except 2 false negatives, has consistently provided informations useful for therapeutic decisions. In 7 cases in critical clinical conditions (refractory heart failure or shock) the echocardiographic examination has afforded the exact documentation and identification of prosthetic pathology, allowing by itself a surgical decision.

摘要

我们回顾性评估了50例有心脏人工瓣膜功能障碍记录患者的临床和超声心动图检查结果。这些人工瓣膜,无论是机械瓣还是生物瓣,二尖瓣位置有24例,主动脉位置有26例。人工瓣膜功能障碍的原因包括血栓形成、纤维钙化变性、纤维织物、细菌感染、裂开、不匹配。临床特征表现为不同程度的心脏功能不全,直至出现对药物治疗无反应的全身性充血性心力衰竭、突然的低输出量综合征、心律失常、心绞痛。听诊结果的变化已成为人工瓣膜功能障碍的重要线索,但我们强调对功能障碍的类型和程度进行仪器记录的必要性。超声心动图是快速、准确地无创诊断人工瓣膜病变的重要工具。超声心动图检查除2例假阴性外,一直能提供有助于治疗决策的信息。在7例处于危急临床状况(难治性心力衰竭或休克)的患者中,超声心动图检查准确记录并识别了人工瓣膜病变,仅凭此即可做出手术决策。

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