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斜视手术中两种不同眼外肌缝合技术的比较

Comparison of Two Different Extraocular Muscle Suturing Techniques for Strabismus Surgery.

作者信息

Zhou Tiantian, Guo Wei, Zhu Xiaoqi, Jing Yu, Shao Qing, Shen Shiya, Chen Xin, Leng Zhenhua, Liu Bin, Zhang Shihua, Xu Wanwen, Liu Hu, Zhu Hui

机构信息

From the Department of Ophthalmology (T.Z., W.G., X.Z., Y.J., Q.S., S.S., Z.L., H.L., H.Z.), The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

Department of Ophthalmology (X.C., B.L., S.Z., W.X.), The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, China.

出版信息

Am J Ophthalmol. 2025 Oct;278:131-139. doi: 10.1016/j.ajo.2025.06.019. Epub 2025 Jun 20.

Abstract

OBJECTIVE

To compare the surgical outcomes after bilateral medial rectus recession (BMR) or bilateral lateral rectus recession (BLR) performed with the 3-point fixation (3PF) vs 2-point fixation (2PF) suturing techniques.

DESIGN

Prospective clinical cohort study.

SUBJECTS

Patients diagnosed with concomitant esotropia or concomitant exotropia and undergoing BMR or BLR with the 3PF or 2PF techniques between January 2022 and January 2025 from the Nanjing Strabismus Cohort Study were included.

METHODS

Postoperative deviation angles were recorded at regular follow-up visits. A Cox proportional hazards model was used to estimate the association between suturing techniques and surgical outcomes.

MAIN OUTCOME MEASURES

The primary outcome was overcorrection, defined as distant eso/exodeviation >10 prism diopters (PD) after BLR or BMR. The secondary outcome was undercorrection/recurrence, defined as distant exo/esodeviation >10 PD after BLR or BMR.

RESULTS

A total of 248 patients were included, with a mean age at surgery of 8.67 ± 6.35 years, of whom 52.42% were male. Of these, 113 underwent surgery with 2PF, and 135 with 3PF. Overcorrection occurred in 27 (10.89%) patients and undercorrection/recurrence occurred in 20 (8.06%) patients. The cumulative incidence of overcorrection was higher in the 2PF group (33.72%; 95% CI, 30.39%-37.22%) compared with the 3PF group (13.09%; 95% CI, 11.71%-14.43%) across the follow-up period (difference: 20.64%, 95% CI, 16.96%-24.28%). Patients in the 3PF group had a 62% decreased risk of overcorrection compared with those in the 2PF group (hazard ratio [HR] = 0.38; 95% CI, 0.16%-0.91%). No significant difference was observed in the cumulative incidence of undercorrection/recurrence between the 2PF group (46.50%; 95% CI, 43.18%-49.96%) and the 3PF group (47.50%; 95% CI, 44.04%-50.99%) over the follow-up period (difference: -1.01%, 95% CI, -5.85% to 3.91%). The suturing technique was not associated with undercorrection/recurrence (HR = 1.07; 95% CI, 0.42%-2.76%).

CONCLUSIONS

These findings support that the 3PF suturing technique is a superior alternative to the 2PF technique for reducing overcorrection in bilateral horizontal rectus muscle recession surgery.

摘要

目的

比较三点固定(3PF)与两点固定(2PF)缝合技术在双侧内直肌后徙术(BMR)或双侧外直肌后徙术(BLR)后的手术效果。

设计

前瞻性临床队列研究。

研究对象

纳入2022年1月至2025年1月期间来自南京斜视队列研究、被诊断为共同性内斜视或共同性外斜视并接受3PF或2PF技术的BMR或BLR手术的患者。

方法

在定期随访时记录术后斜视度。采用Cox比例风险模型评估缝合技术与手术效果之间的关联。

主要观察指标

主要结局为过矫,定义为BLR或BMR术后远距离内/外斜视度>10棱镜度(PD)。次要结局为欠矫/复发,定义为BLR或BMR术后远距离外/内斜视度>10 PD。

结果

共纳入248例患者,手术时平均年龄为8.67±6.35岁,其中52.42%为男性。其中,113例行2PF手术,135例行3PF手术。27例(10.89%)患者发生过矫,20例(8.06%)患者发生欠矫/复发。在整个随访期间,2PF组过矫的累积发生率高于3PF组(33.72%;95%CI,30.39%-37.22%)(差异:20.64%,95%CI,16.96%-24.28%)。与2PF组相比,3PF组患者过矫风险降低62%(风险比[HR]=0.38;95%CI,0.16%-0.91%)。在随访期间,2PF组(46.50%;95%CI,43.18%-49.96%)和3PF组(47.50%;95%CI,44.04%-50.99%)之间欠矫/复发的累积发生率无显著差异(差异:-1.01%,95%CI,-5.85%至3.91%)。缝合技术与欠矫/复发无关(HR = 1.07;95%CI,0.42%-2.76%)。

结论

这些研究结果支持在双侧水平直肌后徙手术中,3PF缝合技术是比2PF技术更好的减少过矫的替代方法。

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