O'Brien Diarmuid, Jabeen Mehwish, El Gammal Amani
Respiratory, Naas General Hospital, Naas, Ireland
HSE Library East, Naas, Ireland.
BMJ Case Rep. 2025 Jun 22;18(6):e265451. doi: 10.1136/bcr-2025-265451.
A woman in her 50s was referred by her general practitioner to the Emergency department for workup of mild hyponatraemia. Her background was significant for an established diagnosis of primary Sjogren's syndrome (pSS), and she was attending a rheumatologist regularly. Further investigations undertaken to establish the cause of her hyponatraemia included CT of the thorax, abdomen and pelvis, which revealed multiple ground glass opacities mostly in the lower lobes. CT-guided biopsy of the lesion in the left lower lobe revealed cores of lung parenchyma with chronic lymphoplasmacytic infiltration and fibrosis. Her case was discussed at the lung multidisciplinary meeting (MDM), and the consensus opinion was a diagnosis of Lymphocytic Interstitial Pneumonia (LIP) based on clinical, radiological and histological evidence. This case illustrates markedly abnormal radiological findings of LIP in a patient with pSS who has remained asymptomatic after a 2 year period of clinical, radiological and physiological monitoring.
一名50多岁的女性被她的全科医生转诊至急诊科，以检查轻度低钠血症。她有确诊的原发性干燥综合征（pSS）病史，并且定期就诊于风湿病专家。为确定其低钠血症病因所进行的进一步检查包括胸部、腹部和骨盆的CT扫描，结果显示多个磨玻璃影，主要位于下叶。对左下叶病变进行的CT引导下活检显示肺实质核心有慢性淋巴细胞浆细胞浸润和纤维化。她的病例在肺部多学科会诊（MDM）上进行了讨论，基于临床、放射学和组织学证据，一致意见是诊断为淋巴细胞间质性肺炎（LIP）。该病例说明了一名pSS患者LIP明显异常的放射学表现，该患者在经过2年的临床、放射学和生理学监测后仍无症状。
