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皮质类固醇与米诺地尔联合治疗促进放射性脱发早期恢复:病例报告

Combined Corticosteroid and Minoxidil Therapy for Early Recovery in Radiation-Induced Alopecia: A Case Report.

作者信息

Chen Xi, Xie Yutong, Wei Aihua

机构信息

Department of Dermatology, Beijing TongRen Hospital, Capital Medical University, Beijing, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2025 Jun 17;18:1495-1499. doi: 10.2147/CCID.S520575. eCollection 2025.

DOI:10.2147/CCID.S520575
PMID:40546991
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12182084/
Abstract

This case report describes a 42-year-old man who developed radiation-induced alopecia after an endovascular embolization procedure for a cerebral arteriovenous fistula. The alopecia appeared as a well-defined patch of hair loss on the right scalp, confirmed by biopsy showing lymphocytic infiltration and increased catagen and telogen follicles. The patient was treated with intramuscular corticosteroid injections and topical 5% minoxidil, leading to complete hair regrowth after three months. Radiation-induced alopecia, though rare and typically self-limiting, requires early diagnosis. This case highlights a novel therapeutic approach combining corticosteroids and minoxidil for faster recovery.

摘要

本病例报告描述了一名42岁男性,在接受脑动静脉瘘血管内栓塞术后出现放射性脱发。脱发表现为右头皮上一块边界清晰的秃发区,活检证实有淋巴细胞浸润以及生长期和休止期毛囊增多。该患者接受了肌肉注射皮质类固醇和外用5%米诺地尔治疗,三个月后头发完全再生。放射性脱发虽然罕见且通常为自限性,但需要早期诊断。本病例突出了一种将皮质类固醇和米诺地尔相结合以实现更快恢复的新型治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f5b/12182084/a3c97452d5d7/CCID-18-1495-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f5b/12182084/3bad9f8bec52/CCID-18-1495-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f5b/12182084/0ec0a327fb44/CCID-18-1495-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f5b/12182084/a3c97452d5d7/CCID-18-1495-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f5b/12182084/3bad9f8bec52/CCID-18-1495-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f5b/12182084/0ec0a327fb44/CCID-18-1495-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f5b/12182084/a3c97452d5d7/CCID-18-1495-g0003.jpg

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本文引用的文献

1
Transient Rectangular Alopecia after Endovascular Embolization: A Case Series of four Patients Describing Dermoscopic and Histopathologic Findings.血管内栓塞术后的短暂性矩形脱发:4例患者的病例系列,描述皮肤镜和组织病理学表现
Int J Trichology. 2022 Jul-Aug;14(4):138-140. doi: 10.4103/ijt.ijt_172_20. Epub 2022 Jul 16.
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Radiation-Induced Rectangular Alopecia after Endovascular Embolization of Cerebral Aneurysms: The Necessity of a Comprehensive Study on Its Incidence and Critical Radiation Doses.脑动脉瘤血管内栓塞术后放射性矩形脱发:对其发生率和临界辐射剂量进行综合研究的必要性
Ann Dermatol. 2019 Aug;31(Suppl):S24-S26. doi: 10.5021/ad.2019.31.S.S24. Epub 2019 Jul 1.
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Single Sitting of Cerebral Endovascular Procedure Causing Alopecia.
单次脑内血管介入手术导致脱发
Int J Trichology. 2018 May-Jun;10(3):145-146. doi: 10.4103/ijt.ijt_11_18.
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Radiation-Induced Alopecia after Endovascular Embolization under Fluoroscopy.透视引导下血管内栓塞术后放射性脱发
Case Rep Dermatol Med. 2016;2016:8202469. doi: 10.1155/2016/8202469. Epub 2016 Dec 15.
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Transitory Rectangular Alopecia After Endovascular Embolization: A Case Report and Description of the Histopathology Findings.血管内栓塞术后的暂时性矩形脱发:一例报告及组织病理学发现描述
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Dermoscopic findings in radiation-induced alopecia after angioembolization.血管栓塞术后放射性脱发的皮肤镜表现
Dermatology. 2014;229(2):141-5. doi: 10.1159/000362810. Epub 2014 Aug 26.
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Square alopecia: a new type of transient alopecia of the scalp following fluoroscopically endovascular embolization.方形脱发:一种透视引导下血管内栓塞术后出现的新型头皮暂时性脱发。
Int J Trichology. 2013 Oct;5(4):201-3. doi: 10.4103/0974-7753.130406.
8
Temporary alopecia after subarachnoid haemorrhage.蛛网膜下腔出血后的暂时性脱发。
J Clin Neurosci. 2007 Feb;14(2):157-61. doi: 10.1016/j.jocn.2005.12.031. Epub 2006 Nov 14.
9
Postoperative alopecia in five patients after treatment of aneurysm rupture with a Guglielmi detachable coil: pressure alopecia, radiation induced, or both?5例使用 Guglielmi 可脱性弹簧圈治疗动脉瘤破裂后的术后脱发:是压力性脱发、放射性脱发,还是两者皆有?
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