Zhang Aifei, Liu Xiaoxia, Wu Pengjia, Qin Longyan, Li Na, Yin Yi, Zeng Jiashun
Department of Rheumatology and Immunology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Department of Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Front Immunol. 2025 Jun 6;16:1557555. doi: 10.3389/fimmu.2025.1557555. eCollection 2025.
Central diabetes insipidus secondary to hypophysitis in eosinophilic granulomatosis with polyangiitis (EGPA) is very rare, and this article summarizes one case reported from our site as well as two previously reported patients with EGPA, both of whom had central diabetes insipidus, suggesting that new, rare organ involvement (pituitary gland) may occur in the early stages of EGPA or years later. The aim is to improve our understanding of central diabetes insipidus caused by EGPA involving the pituitary gland and avoid misdiagnosis or missed diagnosis.
嗜酸性肉芽肿性多血管炎（EGPA）继发垂体炎导致的中枢性尿崩症非常罕见，本文总结了我们医院报告的一例病例以及之前报道的另外两例EGPA患者，这两位患者均患有中枢性尿崩症，提示在EGPA的早期或数年后可能会出现新的、罕见的器官受累（垂体）情况。目的是提高我们对EGPA累及垂体导致中枢性尿崩症的认识，避免误诊或漏诊。
