Chouk Kayri, Triki Raoua, Dergaa Ismail, Ceylan Halil İbrahim, Bougrine Houda, Raul-Ioan Muntean, Ben Abderrahman Abderraouf
High Institute of Sport and Physical Education of Ksar Said, University of Manouba, Manouba, Tunisia.
Physical Education of Sports Teaching Department, Faculty of Sports Sciences, Ataturk University, Erzurum, Türkiye.
Front Endocrinol (Lausanne). 2025 Jun 6;16:1525559. doi: 10.3389/fendo.2025.1525559. eCollection 2025.
Type 2 diabetes mellitus (T2DM) is associated with metabolic and cardiovascular complications. While physical activity and dietary modifications are established interventions, their combined effects in active male populations remain underexplored.
To assess the effects of a 12-week therapeutic diet and/or physical activity program on body composition and biochemical parameters in male recreational athletes with T2DM.
Thirty-six male recreational athletes (aged 30-45 years) with T2DM were randomly assigned to: Physical Activity (PA), Nutritional Regimen (NR), Combined PA and NR (PA+NR), or Control (CG) groups. Body composition (body mass, body fat percentage, muscle mass) and biochemical markers (FBS, HbA1c, LDL-C, HDL-C, HOMA-IR) were measured at baseline, midpoint, and intervention end.
The PA+NR group showed significant improvements in body composition: reduced body mass (p<0.05, ES=0.29), reduced body fat percentage (p<0.05, ES=0.31), and increased muscle mass (p<0.05, ES=0.35). This group also demonstrated significant improvements in biochemical markers: reduced FBS (p<0.05, ES=0.17), HbA1c (p<0.05, ES=0.23), LDL-C (p<0.05, ES=0.17), and HOMA-IR (p<0.05, ES=0.39), with increased HDL-C (p<0.05, ES=0.29). The PA group showed only HbA1c reductions, while the NR group primarily improved lipid profiles. No significant changes occurred in the control group.
A combined therapeutic diet and physical activity program effectively improved body composition and biochemical parameters in recreational athletes with T2DM. This combined approach could be recommended as an integral strategy for diabetes management in physically active individuals.
2型糖尿病(T2DM)与代谢和心血管并发症相关。虽然体育活动和饮食调整是既定的干预措施,但它们在活跃男性人群中的综合作用仍未得到充分研究。
评估为期12周的治疗性饮食和/或体育活动计划对患有T2DM的男性业余运动员身体成分和生化参数的影响。
36名年龄在30 - 45岁之间患有T2DM的男性业余运动员被随机分配到:体育活动(PA)组、营养方案(NR)组、PA与NR联合(PA+NR)组或对照组(CG)。在基线、中期和干预结束时测量身体成分(体重、体脂百分比、肌肉量)和生化指标(空腹血糖、糖化血红蛋白、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、胰岛素抵抗指数)。
PA+NR组在身体成分方面有显著改善:体重减轻(p<0.05,效应量=0.29)、体脂百分比降低(p<0.05,效应量=0.31)、肌肉量增加(p<0.05,效应量=0.35)。该组在生化指标方面也有显著改善:空腹血糖降低(p<0.05,效应量=0.17)、糖化血红蛋白降低(p<0.05,效应量=0.23)、低密度脂蛋白胆固醇降低(p<0.05,效应量=0.17)、胰岛素抵抗指数降低(p<0.05,效应量=0.39),高密度脂蛋白胆固醇升高(p<0.05,效应量=0.29)。PA组仅糖化血红蛋白降低,而NR组主要改善血脂谱。对照组无显著变化。
治疗性饮食和体育活动相结合的方案有效改善了患有T2DM的业余运动员的身体成分和生化参数。这种联合方法可作为体力活动人群糖尿病管理的综合策略推荐。