Suryanarayana Ananthanarayanan Udupi, Balasubramaniam Vidhya Vikashini, Prashanthi Kalisetty, Gochhait Debasis, Pari Hariswar
Department of Pathology, JIPMER, Puducherry, India.
Department of General Medicine, JIPMER, Puducherry, India.
Cytopathology. 2025 Nov;36(6):629-631. doi: 10.1111/cyt.70005. Epub 2025 Jun 23.
Detection of tachyzoites of Toxoplasma gondii in cerebrospinal fluid led to the diagnosis of central nervous system (CNS) toxoplasmosis in a 20 years old male. The cerebrospinal fluid (CSF) was obtained by lumbar puncture and two cytology smears were prepared by cytocentrifugation, one of which was stained with the May-Grünwald Giemsa (MGG) stain and the other with Papanicolaou stain. Light microscopic examination revealed pleocytosis along with numerous intracellular phagocytosed as well as extracellular tachyzoites with cytomorphology characteristic of Toxoplasma gondii. The diagnosis was confirmed by the serological elevation of anti-Toxoplasma IgM levels.
在一名20岁男性患者的脑脊液中检测到刚地弓形虫速殖子，从而确诊为中枢神经系统（CNS）弓形虫病。通过腰椎穿刺获取脑脊液，采用细胞离心法制备两张细胞学涂片，其中一张用迈-格-姬氏（MGG）染色，另一张用巴氏染色。光学显微镜检查显示有细胞增多，伴有大量细胞内吞噬的以及细胞外的速殖子，其细胞形态具有刚地弓形虫的特征。抗弓形虫IgM水平的血清学升高证实了诊断。
