Joseph Luberson, New Emily Margaret, Joseph Desi Marie, Woodley Tamara Chenell, Franco Vanessa Yamileth, Li Ben-Zheng, Wogan Guinevere O U, McCullagh Elizabeth A
Department of Integrative Biology, Oklahoma State University (OSU), College of Arts and Sciences, Stillwater, Oklahoma 74078, USA.
Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.
J Acoust Soc Am. 2025 Jun 1;157(6):4559-4572. doi: 10.1121/10.0036945.
The genus Peromyscus has been extensively used as a model for ecological, behavioral, and evolutionary studies. This study used auditory brainstem responses (ABRs), craniofacial morphology, and pinna measurements to compare two wild-caught species, Peromyscus leucopus and Peromyscus maniculatus. It was observed that P. leucopus exhibited larger features and bigger overall size compared to P. maniculatus. ABR recordings showed similar hearing thresholds with peak sensitivity between 8 and 46 kHz for both species. There were no significant differences between species for absolute amplitudes of waves IV and I, with significantly higher amplitude ratio of wave IV to wave I in P. leucopus across intensities. There were also species differences (faster wave I in P. maniculatus) and sex differences (faster wave I in female P. leucopus) for absolute latency, which were no longer significant when considering inter-peak latency between waves I and IV. Finally, faster normalized latencies of the binaural interaction component (BIC) were observed in P. maniculatus, while no differences were observed across relative BIC amplitude between species. These results provide additional ABR related data that expand the use of both Peromyscus species as future models for auditory research.
白足鼠属已被广泛用作生态、行为和进化研究的模型。本研究使用听觉脑干反应（ABR）、颅面形态和耳廓测量来比较两种野生捕获的物种，即白足鼠（Peromyscus leucopus）和鹿鼠（Peromyscus maniculatus）。观察到，与鹿鼠相比，白足鼠具有更大的特征和更大的整体尺寸。ABR记录显示，两种物种的听力阈值相似，峰值敏感度在8至46kHz之间。物种间波IV和波I的绝对振幅没有显著差异，但在不同强度下，白足鼠的波IV与波I的振幅比显著更高。在绝对潜伏期方面也存在物种差异（鹿鼠的波I更快）和性别差异（雌性白足鼠的波I更快），但在考虑波I和波IV之间的峰间潜伏期时，这些差异不再显著。最后，观察到鹿鼠的双耳相互作用成分（BIC）的归一化潜伏期更快，而物种间相对BIC振幅没有差异。这些结果提供了额外的与ABR相关的数据，扩大了将这两种白足鼠属物种用作未来听觉研究模型的用途。
