Pratt P C, George M H, Mastin J P, Roggli V L
Hum Pathol. 1985 Nov;16(11):1141-6. doi: 10.1016/s0046-8177(85)80183-0.
The subserosal stroma of hernia sacs consistently contains birefringent particulate material, in amounts greater than those observed in other intra-abdominal organs. The major component of this material was shown in the present study to be talc; thus, it cannot be of endogenous origin. Cellular response to this foreign material is remarkably slight. Possible sources of the material and mechanisms of access to the hernia sac were examined in a search of the available literature. It is proposed that the probable source is ingestion with food or, more likely, medications and that the particles reach the peritoneal cavity by migration through the intact intestinal wall. They probably reach the hernia by sedimentation in peritoneal fluid and subsequently migrate into the subserosa. The virtual absence of response to the particles is attributed to their composition (silicate) and their relatively small size (up to about 10 microns) compared with the particles in talc granulomas (up to at least 50 microns).
疝囊的浆膜下基质始终含有双折射颗粒物质，其含量高于在其他腹腔内器官中观察到的含量。本研究表明，这种物质的主要成分是滑石粉；因此，它不可能是内源性的。对这种外来物质的细胞反应非常轻微。通过查阅现有文献，研究了该物质的可能来源和进入疝囊的机制。有人提出，可能的来源是随食物摄入，或者更有可能是药物摄入，并且颗粒通过完整的肠壁迁移到达腹膜腔。它们可能通过在腹膜液中沉降到达疝囊，随后迁移到浆膜下。对这些颗粒几乎没有反应归因于它们的成分（硅酸盐）以及与滑石肉芽肿中的颗粒（至少达50微米）相比相对较小的尺寸（达约10微米）。
