Study on the safety and effectiveness of CSP and HSP-EMR in small polyps colorectal cancer in the elderly population: Randomized controlled trial.

BACKGROUND

This study evaluates the safety and efficacy of cold snare polypectomy (CSP) and hot snare polypectomy endoscopic mucosal resection (HSP-EMR) for small sessile colorectal polyps in the elderly population.

METHODS

Patients with small sessile colorectal polyps were randomized to either CSP or HSP-EMR, including 80 patients in the observation group (CSP) and 125 patients in the control group (HSP-EMR). General data, titanium clip utilization rates, complete resection rates, immediate bleeding rates, specimen recovery rates, incidence of delayed bleeding, perforation rates, and incidence of abdominal discomfort were compared between the 2 groups.

RESULTS

There were no significant differences in the distribution of general data (age, gender, location, morphology, and pathological type) or underlying diseases (hypertension and diabetes) between the 2 groups (P > .05). There were no significant differences in the complete resection rate, specimen recovery rate, or delayed bleeding rate between the 2 groups (P > .05). The utilization rate of titanium clips and the incidence of abdominal discomfort in the observation group were significantly lower than those in the control group. The immediate bleeding rate was higher in the observation group than that in the control group. The difference between the 2 groups was statistically significant (P < .05). No perforation occurred in either of the groups. Group discussion was conducted according to whether postoperative complications occurred. Univariate and binary logistic regression analysis was used to analyze the risk factors of postoperative complications. The average polyp diameter, body mass index and surgical method were independent risk factors for postoperative complications (P < .05).

CONCLUSION

CSP and HSP-EMR are safe and efficacy in the treatment of small sessile colorectal polyps in elderly people. For overweight and obese people with large polyps, HSP-EMR patients should be closely observed for postoperative complications.