Singh V S
Indian J Physiol Pharmacol. 1985 Jan-Mar;29(1):51-4.
The serum phosphohexose isomerase (PHI), aldolase and hexokinase activities have been determined in 36 patients of carcinoma ovary with different clinical stages and in 25 healthy normal female subjects. The serum PHI and hexokinase levels were significantly elevated (P less than .001) in all the stages of malignancy while serum aldolase was significantly elevated only in stages III and IV of malignancy. The enzyme levels showed statistically significant response to therapy in stage II patients. The mean values in patients with progression of the disease were not significantly different.
已对36例不同临床分期的卵巢癌患者和25名健康正常女性受试者测定了血清磷酸己糖异构酶（PHI）、醛缩酶和己糖激酶活性。在所有恶性肿瘤阶段，血清PHI和己糖激酶水平均显著升高（P＜0.001），而血清醛缩酶仅在恶性肿瘤的III期和IV期显著升高。II期患者的酶水平对治疗有统计学意义的反应。疾病进展患者的平均值无显著差异。
