含有四氯化碳和NADPH的需氧微粒体孵育中形成的自由基的表征。 - Suppr

Suppr

超能文献

Characterization of the free radical formed in aerobic microsomal incubations containing carbon tetrachloride and NADPH.

作者信息

Kalyanaraman B, Mason R P, Perez-Reyes E, Chignell C F, Wolf C R, Philpot R M

出版信息

Biochem Biophys Res Commun. 1979 Aug 28;89(4):1065-72. doi: 10.1016/0006-291x(79)92116-8.

DOI:10.1016/0006-291x(79)92116-8

PMID:40551

Abstract

摘要

相似文献

Characterization of the free radical formed in aerobic microsomal incubations containing carbon tetrachloride and NADPH.含有四氯化碳和NADPH的需氧微粒体孵育中形成的自由基的表征。

Biochem Biophys Res Commun. 1979 Aug 28;89(4):1065-72. doi: 10.1016/0006-291x(79)92116-8.

Clarification of the relationship between free radical spin trapping and carbon tetrachloride metabolism in microsomal systems.微粒体系统中自由基自旋捕获与四氯化碳代谢之间关系的阐明。

Free Radic Biol Med. 1998 Jun;24(9):1364-8. doi: 10.1016/s0891-5849(97)00460-7.

Radical activation of carbon tetrachloride in foetal and maternal rat liver microsomes.四氯化碳在胎鼠和母鼠肝脏微粒体中的自由基活化作用。

Biochem Pharmacol. 1986 Jun 15;35(12):2041-4. doi: 10.1016/0006-2952(86)90739-2.

Confirmation of assignment of the trichloromethyl radical spin adduct detected by spin trapping during 13C-carbon tetrachloride metabolism in vitro and in vivo.通过自旋捕集法检测到的三氯甲基自由基自旋加合物在四氯化碳体外和体内代谢过程中归属的确证。

Biochem Biophys Res Commun. 1980 Jun 30;94(4):1154-60. doi: 10.1016/0006-291x(80)90540-9.

An update on antioxidant theory: spin trapping of trichloromethyl radicals in vivo.抗氧化理论的更新：体内三氯甲基自由基的自旋捕获

Ann N Y Acad Sci. 1982;393:23-31. doi: 10.1111/j.1749-6632.1982.tb31229.x.

Spin-trapping studies on the free-radical products formed by metabolic activation of carbon tetrachloride in rat liver microsomal fractions isolated hepatocytes and in vivo in the rat.对四氯化碳在大鼠肝微粒体组分、分离的肝细胞以及大鼠体内经代谢活化形成的自由基产物的自旋捕集研究。

Biochem J. 1982 May 15;204(2):593-603. doi: 10.1042/bj2040593.

Reductive oxygenation of carbon tetrachloride: trichloromethylperoxyl radical as a possible intermediate in the conversion of carbon tetrachloride to electrophilic chlorine.四氯化碳的还原氧化作用：三氯甲基过氧自由基作为四氯化碳转化为亲电氯过程中的一种可能中间体。

Arch Biochem Biophys. 1983 Sep;225(2):596-609. doi: 10.1016/0003-9861(83)90071-1.

Cytochrome P-450-dependent formation of reactive oxygen radicals: isozyme-specific inhibition of P-450-mediated reduction of oxygen and carbon tetrachloride.细胞色素P - 450依赖性活性氧自由基的形成：P - 450介导的氧还原和四氯化碳的同工酶特异性抑制作用

Xenobiotica. 1990 Sep;20(9):887-900. doi: 10.3109/00498259009046904.

Spin-trapping of the trichloromethyl radical produced during enzymic NADPH oxidation in the presence of carbon tetrachloride or bromotrichloromethane.

Biochim Biophys Acta. 1978 Mar 20;539(3):402-9. doi: 10.1016/0304-4165(78)90044-2.

4-(4-R-phenylamino)-5-methoxy-1,2-benzoquinones are new selective inhibitors of carbon tetrachloride-initiated free radical reactions in liver.

Biochem Int. 1991 Sep;25(1):167-72.

引用本文的文献

Tandem mass spectrometry study of C-phenyl-N-tert-butyl nitrone spin adducts from in vitro rat liver microsomal metabolism of bromotrichloromethane and carbon tetrachloride.串联质谱法研究溴三氯甲烷和四氯化碳在体外大鼠肝微粒体代谢中的 C-苯-N-叔丁基硝酮自旋加合物。

J Am Soc Mass Spectrom. 1995 Sep;6(9):847-53. doi: 10.1016/1044-0305(95)00328-B.

Differential effects of partial hepatectomy and carbon tetrachloride administration on induction of liver cell foci in a model for detection of initiation activity.在一个用于检测启动活性的模型中，部分肝切除术和给予四氯化碳对肝细胞灶诱导的不同影响。

Jpn J Cancer Res. 2001 Oct;92(10):1018-25. doi: 10.1111/j.1349-7006.2001.tb01055.x.

Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine.在磷脂囊泡中重组的人细胞色素P-450对四氯化碳的还原代谢：与二油酰磷脂酰胆碱结合的三氯甲基自由基的质谱鉴定

Proc Natl Acad Sci U S A. 1982 Apr;79(8):2678-82. doi: 10.1073/pnas.79.8.2678.

Biochem J. 1982 May 15;204(2):593-603. doi: 10.1042/bj2040593.

Application of ESR spectroscopy in toxicology.电子自旋共振光谱在毒理学中的应用。

Arch Toxicol. 1987;60(1-3):133-7. doi: 10.1007/BF00296966.

Biochemical studies on the metabolic activation of halogenated alkanes.卤代烷烃代谢活化的生化研究。

Environ Health Perspect. 1985 Dec;64:85-101. doi: 10.1289/ehp.856485.

Involvement of free radicals in the mechanism of 3-methylindole-induced pulmonary toxicity: an example of metabolic activation in chemically induced lung disease.自由基在3-甲基吲哚诱导的肺毒性机制中的作用：化学诱导的肺部疾病中代谢活化的一个例子。

Environ Health Perspect. 1985 Dec;64:61-7. doi: 10.1289/ehp.856461.

Chemistry and biology of spin-trapping radicals associated with halocarbon metabolism in vitro and in vivo.体外和体内与卤代烃代谢相关的自旋捕获自由基的化学与生物学特性

Environ Health Perspect. 1985 Dec;64:151-70. doi: 10.1289/ehp.8564151.

Ethanol and food deprivation induced enhancement of hepatotoxicity in rats given carbon tetrachloride at low concentration.乙醇和食物剥夺会增强低浓度四氯化碳处理的大鼠的肝毒性。

Br J Ind Med. 1991 Sep;48(9):636-42. doi: 10.1136/oem.48.9.636.

Radical adducts of nitrosobenzene and 2-methyl-2-nitrosopropane with 12,13-epoxylinoleic acid radical, 12,13-epoxylinolenic acid radical and 14,15-epoxyarachidonic acid radical. Identification by h.p.l.c.-e.p.r. and liquid chromatography-thermospray-m.s.亚硝基苯和2-甲基-2-亚硝基丙烷与12,13-环氧亚油酸自由基、12,13-环氧亚麻酸自由基和14,15-环氧花生四烯酸自由基的自由基加合物。通过高效液相色谱-电子顺磁共振和液相色谱-热喷雾-质谱进行鉴定

Biochem J. 1991 Jun 1;276 ( Pt 2)(Pt 2):447-53. doi: 10.1042/bj2760447.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验