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抑郁在纤维肌痛患者感知到的不公正与疼痛强度关系中的中介作用。

The Mediating Role of Depression in the Relationship Between Perceived Injustice and Pain Intensity Among Fibromyalgia Patients.

作者信息

Raev Sheer, Aloush Valerie, Gilam Gadi, Elkana Odelia

机构信息

Behavioral Sciences, Academic College of Tel Aviv-Yaffo, Tel Aviv, Israel.

Institute of Rheumatology and Internal Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv-Yaffo, Israel.

出版信息

J Pain Res. 2025 Jun 19;18:3077-3085. doi: 10.2147/JPR.S518357. eCollection 2025.

Abstract

BACKGROUND

Fibromyalgia (FM) patients often perceive heightened levels of injustice, which can be associated with depressive symptoms. Despite this connection, the mediating role of depression between perceived injustice and pain intensity in FM patients remains unexplored.

AIM

This study explored whether depression mediates the relationship between perceived injustice and pain intensity in FM.

METHODS

Data were collected through an online survey distributed to FM patients at the Tel Aviv Sourasky Medical Center, Israel. A total of 161 FM patients completed the survey, with perceived injustice assessed using the Injustice Experience Questionnaire, depression evaluated using the Patient Health Questionnaire, and pain intensity measured with the numerical Pain Intensity Rating Scale. Statistical analyses included analysis of variance and bootstrap-based mediation models.

RESULTS

FM patients reported elevated levels of pain, perceived injustice, and depression. The study found that depression significantly mediated the association between perceived injustice and pain intensity in FM patients (P < 0.001, CI = 0.024, 0.312).

CONCLUSION

The link between perceived injustice and pain intensity in FM is partially explained by the level of depression. Individuals with higher perceived injustice scores are more susceptible to depression, subsequently experiencing increased pain. These findings suggest that intervention programs targeting depression may mitigate the impact of perceived injustice on pain intensity in FM, potentially enhancing health-related quality of life.

摘要

背景

纤维肌痛(FM)患者常常感觉自己遭受了更多的不公正对待,这可能与抑郁症状有关。尽管存在这种联系,但在FM患者中,抑郁在感知到的不公正与疼痛强度之间的中介作用仍未得到探索。

目的

本研究探讨抑郁是否在FM患者感知到的不公正与疼痛强度之间起中介作用。

方法

通过在线调查收集数据,该调查面向以色列特拉维夫索拉斯基医疗中心的FM患者。共有161名FM患者完成了调查,使用不公正经历问卷评估感知到的不公正,使用患者健康问卷评估抑郁,并用数字疼痛强度评分量表测量疼痛强度。统计分析包括方差分析和基于自抽样法的中介模型。

结果

FM患者报告的疼痛、感知到的不公正和抑郁水平均有所升高。研究发现,抑郁在FM患者感知到的不公正与疼痛强度之间的关联中起显著中介作用(P < 0.001,CI = 0.024,0.312)。

结论

FM患者感知到的不公正与疼痛强度之间的联系部分可由抑郁水平来解释。感知到的不公正得分较高的个体更容易患抑郁症,进而经历更强烈的疼痛。这些发现表明,针对抑郁的干预项目可能会减轻FM患者感知到的不公正对疼痛强度的影响,从而有可能提高与健康相关的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bd8/12184704/2c11e93e9939/JPR-18-3077-g0001.jpg

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