Wang Yan, Chen Yong, Zhang Bo, Liu Xianfu
Department of Surgical Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, China.
Br J Hosp Med (Lond). 2025 Jun 25;86(6):1-9. doi: 10.12968/hmed.2024.1013. Epub 2025 Jun 24.
Bilateral breast cancer (BBC) is an uncommon subtype of breast cancer which occurs either synchronously or metachronously. Synchronous BBC with distinct histological types in the left and right breasts is particularly rare. This report presents a case of a 57-year-old female patient diagnosed with bilateral primary breast cancer, characterized by ductal carcinoma (DCIS) in one breast and invasive ductal carcinoma (IDC) in the other. The patient initially sought medical attention due to a palpable mass and pain in her left breast, leading to a diagnosis confirmed through imaging studies and biopsy. The patient was treated with three cycles of neoadjuvant therapy, followed by a modified radical mastectomy on the left breast and a lumpectomy on the right breast. Postoperatively, the patient received endocrine therapy and radiotherapy, with no evidence of recurrence observed to date. Further research and clinical advancements are necessary to optimize treatment and care strategies for patients with bilateral breast cancer, ensuring that their unique therapeutic needs are effectively addressed.
双侧乳腺癌（BBC）是一种不常见的乳腺癌亚型，可同时或异时发生。左右乳房具有不同组织学类型的同时性BBC尤为罕见。本报告介绍了一例57岁女性患者，被诊断为双侧原发性乳腺癌，其特征为一侧乳房为导管原位癌（DCIS），另一侧为浸润性导管癌（IDC）。患者最初因左侧乳房可触及肿块和疼痛就医，经影像学检查和活检确诊。患者接受了三个周期的新辅助治疗，随后左侧乳房行改良根治性乳房切除术，右侧乳房行肿块切除术。术后，患者接受了内分泌治疗和放疗，迄今为止未观察到复发迹象。有必要进行进一步的研究和临床进展，以优化双侧乳腺癌患者的治疗和护理策略，确保有效满足他们独特的治疗需求。
