Weems D H, Mendenhall W M, Bova F J, Marcus R B, Morgan L S, Million R R
Int J Radiat Oncol Biol Phys. 1985 Nov;11(11):1911-4. doi: 10.1016/0360-3016(85)90271-8.
This is an analysis of 123 patients with Stage IB-IIA-B carcinoma of the intact uterine cervix, 6 cm or greater in diameter, who were treated with curative intent at the University of Florida with radiation alone or radiation followed by a hysterectomy between October 1964 and February 1982. There is a minimum follow-up of 2 years in all patients; 87% of all recurrences and 91% of pelvic recurrences occurred within this time period. Examination of pelvic control rates, as well as disease-free survival, showed no significant advantage in pelvic control, disease-free survival, or absolute survival for either treatment group when compared by stage and tumor size. The incidence of severe complications was 6% for patients treated with irradiation alone and 15% for those treated with irradiation and surgery (p = 0.119).
这是一项对123例直径6厘米或更大的完整子宫颈IB-IIA-B期癌患者的分析，这些患者于1964年10月至1982年2月在佛罗里达大学接受了单纯放疗或放疗后子宫切除术的根治性治疗。所有患者的最短随访时间为2年；所有复发中的87%和盆腔复发中的91%发生在这一时间段内。通过分期和肿瘤大小比较，两组治疗在盆腔控制率、无病生存率或绝对生存率方面均未显示出显著优势。单纯放疗患者的严重并发症发生率为6%，放疗加手术患者为15%（p = 0.119）。
