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Epithelial Abnormalities in the High-Risk Fallopian Tube of a Rare / Li-Fraumeni Syndrome Patient With Multiple Tumors.

作者信息

Ritting Megan L, Warring Simrit K, Bettencourt Manuel M, Musheer Aalam Syed Mohammed, Shahi Maryam, Couch Fergus J, Bakkum-Gamez Jamie N, Kannan Nagarajan

机构信息

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.

Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN.

出版信息

JCO Precis Oncol. 2025 Jun;9:e2400589. doi: 10.1200/PO-24-00589. Epub 2025 Jun 24.

DOI:10.1200/PO-24-00589
PMID:40554737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12184977/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8213/12184977/fe9cfee3f026/po-9-e2400589-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8213/12184977/a380e24fc103/po-9-e2400589-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8213/12184977/2b8949fccdec/po-9-e2400589-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8213/12184977/fe9cfee3f026/po-9-e2400589-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8213/12184977/a380e24fc103/po-9-e2400589-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8213/12184977/2b8949fccdec/po-9-e2400589-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8213/12184977/fe9cfee3f026/po-9-e2400589-g003.jpg

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本文引用的文献

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Gynecol Oncol Rep. 2024 Mar 5;52:101359. doi: 10.1016/j.gore.2024.101359. eCollection 2024 Apr.
2
Ovarian cancer mutational processes drive site-specific immune evasion.卵巢癌突变过程驱动特定部位的免疫逃逸。
Nature. 2022 Dec;612(7941):778-786. doi: 10.1038/s41586-022-05496-1. Epub 2022 Dec 14.
3
Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq.
使用 scRNA-seq 鉴定正常和输卵管积水疾病状态下人类输卵管的细胞异质性。
Dev Cell. 2022 Apr 11;57(7):914-929.e7. doi: 10.1016/j.devcel.2022.02.017. Epub 2022 Mar 22.
4
Risk-Reducing Bilateral Salpingo-Oophorectomy for Ovarian Cancer: A Review and Clinical Guide for Hereditary Predisposition Genes.降低风险的双侧输卵管卵巢切除术用于卵巢癌：遗传性易感性基因的综述和临床指南。
JCO Oncol Pract. 2022 Mar;18(3):201-209. doi: 10.1200/OP.21.00382. Epub 2021 Sep 28.
5
Characterizing TP53 mutations in ovarian carcinomas with and without concurrent BRCA1 or BRCA2 mutations.分析伴有或不伴有同时性 BRCA1 或 BRCA2 突变的卵巢癌中的 TP53 突变情况。
Gynecol Oncol. 2021 Mar;160(3):786-792. doi: 10.1016/j.ygyno.2020.12.007. Epub 2020 Dec 26.
6
Loss of tubal ciliated cells as a risk for "ovarian" or pelvic serous carcinoma.输卵管纤毛细胞缺失作为“卵巢”或盆腔浆液性癌的一个风险因素。
Am J Cancer Res. 2020 Nov 1;10(11):3815-3827. eCollection 2020.
7
The Origin of Ovarian Cancer Species and Precancerous Landscape.卵巢癌种的起源与癌前景观。
Am J Pathol. 2021 Jan;191(1):26-39. doi: 10.1016/j.ajpath.2020.09.006. Epub 2020 Oct 1.
8
Guidelines for the Li-Fraumeni and heritable TP53-related cancer syndromes.Li-Fraumeni 及可遗传性 TP53 相关癌症综合征指南。
Eur J Hum Genet. 2020 Oct;28(10):1379-1386. doi: 10.1038/s41431-020-0638-4. Epub 2020 May 26.
9
High grade serous ovarian carcinomas originate in the fallopian tube.高级别浆液性卵巢癌起源于输卵管。
Nat Commun. 2017 Oct 23;8(1):1093. doi: 10.1038/s41467-017-00962-1.
10
Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers.BRCA1 和 BRCA2 基因突变携带者的乳腺癌、卵巢癌和对侧乳腺癌风险。
JAMA. 2017 Jun 20;317(23):2402-2416. doi: 10.1001/jama.2017.7112.