Lee Sunghan, Zheng Guangyao, Koh Jeonghwan, Li Haoran, Xu Zicheng, Cho Sung Pil, Im Sung Il, Braverman Vladimir, Jeong In Cheol
Cerebrovascular Disease Research Center, Hallym University, Chuncheon, 24252, Republic of Korea.
Department of Computer Science, Rice University, Houston, TX, 77005, USA.
Comput Methods Programs Biomed. 2025 Sep;269:108898. doi: 10.1016/j.cmpb.2025.108898. Epub 2025 Jun 18.
Cardiac arrhythmias, characterized by irregular heartbeats, are difficult to diagnose in real-world scenarios. Machine learning has advanced arrhythmia detection; however, the optimal number of heartbeats for precise classification remains understudied. This study addresses this using machine learning while assessing the performance of arrhythmia detection across inter-patient and intra-patient conditions. Furthermore, the performance-resource trade-offs are evaluated for practical deployment in mobile health (mHealth) applications.
Beat-wise segmentation and resampling techniques were utilized for preprocessing electrocardiography (ECG) signals to ensure consistent input lengths. A 1-D convolutional neural network was used to classify the eight multi-labeled arrhythmias. The dataset comprised real-world ECG recordings from the HiCardi wireless device alongside data from the MIT-BIH Arrhythmia database. Model performance was assessed through fivefold cross-validation under both inter-patient and intra-patient conditions.
The proposed model demonstrated peak accuracy at four beats under inter-patient conditions, with minimal improvements beyond this point. This configuration achieved a balance between performance (94.82% accuracy) and resource consumption (training time: 72.27 s per epoch; prediction time: 155 μs per segment). Real-world simulations validated the feasibility of real-time arrhythmia detection for approximately 5000 patients.
Utilizing four heartbeats as the input size for arrhythmia classification results in a trade-off between accuracy and computational efficiency. This discovery has significant implications for real-time wearable ECG devices, where both performance and resource constraints are crucial considerations. This insight is expected to serve as a valuable reference for enhancing the design and implementation of arrhythmia detection systems for scalable and efficient mHealth applications.
心律失常表现为心跳不规则,在实际场景中难以诊断。机器学习推动了心律失常检测的发展;然而,用于精确分类的最佳心跳次数仍未得到充分研究。本研究通过机器学习解决这一问题,同时评估心律失常检测在患者间和患者内条件下的性能。此外,还评估了性能与资源的权衡,以便在移动健康(mHealth)应用中进行实际部署。
采用逐搏分割和重采样技术对心电图(ECG)信号进行预处理,以确保输入长度一致。使用一维卷积神经网络对八种多标签心律失常进行分类。数据集包括来自HiCardi无线设备的实际ECG记录以及来自麻省理工学院 - 贝斯以色列女执事医疗中心心律失常数据库的数据。在患者间和患者内条件下,通过五折交叉验证评估模型性能。
所提出的模型在患者间条件下,在四个心跳时表现出最高准确率,超过此点后改善极小。这种配置在性能(准确率94.82%)和资源消耗(训练时间:每轮72.27秒;预测时间:每段155微秒)之间实现了平衡。实际模拟验证了对约5000名患者进行实时心律失常检测的可行性。
将四个心跳作为心律失常分类的输入大小会在准确性和计算效率之间进行权衡。这一发现对实时可穿戴ECG设备具有重要意义,在这类设备中,性能和资源限制都是关键考虑因素。这一见解有望为增强心律失常检测系统的设计和实施提供有价值的参考,以实现可扩展且高效的移动健康应用。