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用于急性缺血性卒中机械取栓的支架取栓器类型:一项范围综述。

Types of stent retrievers used in mechanical thrombectomy for acute ischaemic stroke: A scoping review.

作者信息

Song Jane, Zhou Kevin Z, Pavlin-Premrl Davor, Jhamb Ashu, Gan Calvin, Khabaza Ali, Maingard Julian, Gauden Andrew, Slater Lee-Anne, Moore Justin, Kutaiba Numan, Chandra Ronil V, Yazdabadi Anousha, Brooks Mark D, Kok Hong Kuan, Barras Christen, Asadi Hamed

机构信息

Department of Radiology, Austin Health, Melbourne, Australia.

Department of Radiology, Austin Health, Melbourne, Australia; Interventional Neuroradiology Service, Department of Radiology, St Vincent's Health, Melbourne, Australia.

出版信息

J Clin Neurosci. 2025 Aug;138:111412. doi: 10.1016/j.jocn.2025.111412. Epub 2025 Jun 23.

Abstract

Mechanical thrombectomy using stent retrievers is the standard endovascular treatment for acute ischaemic stroke due to large vessel occlusion. With the rapid evolution in device design, this scoping review aims to map the current landscape of stent retriever types used in clinical practice, as well as their application across different sites of vessel occlusion. A comprehensive literature search was conducted using MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials to identify primary studies reporting on the safety and efficacy of stent retrievers in mechanical thrombectomy for acute stroke. After screening and data extraction by two independent reviewers, 133 studies were included, encompassing 22 distinct stent retriever devices. Frequencies of thrombectomy procedures were analysed according to device type and occlusion location. The Solitaire and Trevo devices accounted for the majority of cases (57 %), with the most commonly treated occlusion sites being the M1 segment of the middle cerebral artery and the internal carotid artery (51 % and 19 %, respectively). In contrast, anterior cerebral artery and M3 or more distal occlusions were underrepresented, each comprising only 1 % of the data. This review highlights a strong evidence base for conventional stent retrievers in large vessel occlusions, particularly M1, while also revealing a significant gap in knowledge regarding newer generation stent retrievers and their use in distal medium vessel occlusions. Further research is needed to evaluate device safety and effectiveness in these smaller, more challenging vessels.

摘要

使用支架取栓器进行机械取栓是治疗大血管闭塞所致急性缺血性卒中的标准血管内治疗方法。随着器械设计的迅速发展,本综述旨在梳理临床实践中使用的支架取栓器类型的现状,以及它们在不同血管闭塞部位的应用情况。我们使用MEDLINE、Embase和Cochrane对照试验中央注册库进行了全面的文献检索,以确定关于支架取栓器在急性卒中机械取栓中的安全性和有效性的原始研究。在两名独立评审员进行筛选和数据提取后,纳入了133项研究,涵盖22种不同的支架取栓器装置。根据器械类型和闭塞位置分析了取栓手术的频率。Solitaire和Trevo装置占大多数病例(57%),最常治疗的闭塞部位是大脑中动脉M1段和颈内动脉(分别为51%和19%)。相比之下,大脑前动脉以及M3段或更远端的闭塞情况代表性不足,每种情况仅占数据的1%。本综述强调了传统支架取栓器在大血管闭塞(尤其是M1段)方面有强有力的证据基础,同时也揭示了关于新一代支架取栓器及其在远端中等血管闭塞中的应用存在显著的知识空白。需要进一步研究来评估这些较小且更具挑战性的血管中器械的安全性和有效性。

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