Freeman K P, Monlux A W, Heald D, Sealock M C
J Am Vet Med Assoc. 1985 Oct 15;187(8):838-9.
Clinical signs of bradycardia and syncope, associated with intracranial meningioma, were observed in a 4-year-old female Irish Setter. Electrocardiographic abnormalities confirming bradycardia and suggestive of sinoatrial arrest were demonstrated. Return to a normal heart rate and sinus rhythm after administration of atropine IV indicated that increased vagal tone was responsible for the observed abnormalities. Neither glycopyrrolate nor propantheline bromide therapy was successful in controlling bradycardia and syncope. Necropsy findings included the demonstration of a 3 X 2 X 2-cm mass on the ventral aspect of the right half of the brain. This mass covered half of the mammillary body and extended as a thick reddish brown membrane extending over the piriform lobe of the cerebrum, optic chiasm, and longitudinal fissure. Histologically, the mass was identified as a meningotheliomatous meningioma.
在一只4岁雌性爱尔兰赛特犬身上观察到与颅内脑膜瘤相关的心动过缓和晕厥的临床症状。心电图异常证实了心动过缓并提示窦性停搏。静脉注射阿托品后心率恢复正常且窦性心律表明迷走神经张力增加是观察到的异常的原因。格隆溴铵和溴丙胺太林治疗均未能成功控制心动过缓和晕厥。尸检结果包括在右脑右半侧腹侧发现一个3×2×2厘米的肿块。这个肿块覆盖了乳头体的一半,并作为一层厚厚的红棕色膜延伸,覆盖大脑梨状叶、视交叉和大脑纵裂。组织学上,该肿块被鉴定为脑膜皮型脑膜瘤。