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在2025年欧洲抗风湿病联盟/美国风湿病学会(EULAR/ACR)会议之前,我们在类风湿关节炎管理方面处于什么位置?

Where Do We Stand in the Management of Rheumatoid Arthritis Ahead of EULAR/ACR 2025?

作者信息

Vlad Adriana Liliana, Popazu Corina, Lescai Alina-Maria, Voinescu Doina Carina, Baltă Alexia Anastasia Ștefania

机构信息

Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galați, 800008 Galați, Romania.

"St. Apostle Andrei" Clinical Emergency County Hospital, 800578 Galați, Romania.

出版信息

Clin Pract. 2025 May 28;15(6):103. doi: 10.3390/clinpract15060103.

DOI:10.3390/clinpract15060103
PMID:40558221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12192006/
Abstract

: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by systemic inflammation and the progressive damage of joints, significantly impacting patients' quality of life. Managing this condition requires a complex approach that integrates pharmacological and non-pharmacological therapies, alongside psychosocial support and patient education. Aim: This study aims to highlight the importance of an interdisciplinary approach in the treatment of rheumatoid arthritis, focusing on the role of pharmacological therapies, monitoring treatment response, and the involvement of a multidisciplinary team in the effective management of the disease. : The analysis was based on a review of the specialised literature concerning the role of disease-modifying antirheumatic drugs (DMARDs, both conventional and biological), the use of inflammatory markers (CRP and ESR), advanced imaging techniques, and the contribution of various medical specialities to the holistic management of rheumatoid arthritis. A total of 595,900 records were identified, of which 53 studies were ultimately included in the detailed analysis. Relevant studies from fields such as rheumatology, nutrition, psychology, and physical therapy were included. : The findings underline that DMARDs, in combination with other pharmacological therapies, remain essential for slowing disease progression. Monitoring treatment response through inflammatory markers and imaging techniques allows for the adjustment of therapeutic strategies and the prevention of complications. An interdisciplinary approach, involving the rheumatologist, general practitioner, physiotherapist, nutritionist, and psychologist, provides significant benefits, such as reducing inflammation, improving joint function, and offering psychosocial support. : The effective management of rheumatoid arthritis requires a personalised interdisciplinary approach. Integrating various specialities, along with patient education and psychosocial support, contributes to better disease management, the prevention of disabilities, and improved quality of life. This review is not registered.

摘要

类风湿性关节炎(RA)是一种慢性自身免疫性疾病,其特征为全身性炎症和关节的进行性损伤,对患者的生活质量有显著影响。管理这种疾病需要一种综合药物治疗和非药物治疗的复杂方法,同时还需要心理社会支持和患者教育。目的:本研究旨在强调多学科方法在类风湿性关节炎治疗中的重要性,重点关注药物治疗的作用、监测治疗反应以及多学科团队在该疾病有效管理中的参与。分析基于对有关改善病情抗风湿药(DMARDs,包括传统和生物制剂)的作用、炎症标志物(CRP和ESR)的使用、先进成像技术以及各种医学专科对类风湿性关节炎整体管理的贡献的专业文献的综述。共识别出595,900条记录,其中53项研究最终纳入详细分析。纳入了风湿病学、营养学、心理学和物理治疗等领域的相关研究。研究结果强调,DMARDs与其他药物治疗相结合,对于减缓疾病进展仍然至关重要。通过炎症标志物和成像技术监测治疗反应有助于调整治疗策略并预防并发症。一种包括风湿病学家、全科医生、物理治疗师、营养师和心理学家的多学科方法带来了显著益处,如减轻炎症、改善关节功能以及提供心理社会支持。类风湿性关节炎的有效管理需要个性化的多学科方法。整合各个专科,以及患者教育和心理社会支持,有助于更好地管理疾病、预防残疾并提高生活质量。本综述未注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/815d/12192006/bca68535dfc1/clinpract-15-00103-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/815d/12192006/37c84e6ff498/clinpract-15-00103-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/815d/12192006/3d4a787a3f1e/clinpract-15-00103-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/815d/12192006/bca68535dfc1/clinpract-15-00103-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/815d/12192006/37c84e6ff498/clinpract-15-00103-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/815d/12192006/3d4a787a3f1e/clinpract-15-00103-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/815d/12192006/bca68535dfc1/clinpract-15-00103-g003.jpg

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