Nguyen Dung N Q, Ho Dung Thuong, Tran Thanh N H
Faculty of Medicine, University of Health Sciences, Viet Nam National University, Ho Chi Minh City 7000, Vietnam.
Thong Nhat Hospital, Ho Chi Minh City 7000, Vietnam.
Med Sci (Basel). 2025 May 22;13(2):63. doi: 10.3390/medsci13020063.
This study aims to investigate the correlation between the morphological and functional characteristics of the left atrial appendage (LAA) and the incidence of thromboembolic events by transesophageal echocardiography (TEE) in patients with acute ischemic stroke. : This cross-sectional study included 171 patients with acute ischemic stroke, running from November 2022 to September 2024. Transesophageal echocardiography was performed to evaluate the presence of LAA thrombus. Multivariable logistic regression analysis was performed to identify risk factors for LAA thrombus. Of the 171 patients, 19 (11.1%) were found to have LAA thrombus. Multivariable logistic regression identified two independent predictors of LAA thrombus formation: (1) left atrial spontaneous echo contrast (OR = 8, 95% CI: 3-19, < 0.001) and (2) atrial fibrillation (OR = 8, 95% CI: 1.057-76.095, = 0.044). Left atrial spontaneous echo contrast and atrial fibrillation are independent predictors of LAA thrombus in patients with acute ischemic stroke. The use of transesophageal echocardiography for early detection of LAA thrombus may help improve treatment strategies and prevent recurrent strokes.
本研究旨在通过经食管超声心动图（TEE）探讨急性缺血性脑卒中患者左心耳（LAA）的形态和功能特征与血栓栓塞事件发生率之间的相关性。这项横断面研究纳入了2022年11月至2024年9月期间的171例急性缺血性脑卒中患者。通过经食管超声心动图评估LAA血栓的存在情况。进行多变量逻辑回归分析以确定LAA血栓的危险因素。在这171例患者中，发现19例（11.1%）存在LAA血栓。多变量逻辑回归确定了LAA血栓形成的两个独立预测因素：（1）左心房自发显影（OR = 8，95%CI：3 - 19，<0.001）和（2）心房颤动（OR = 8，95%CI：1.057 - 76.095，= 0.044）。左心房自发显影和心房颤动是急性缺血性脑卒中患者LAA血栓的独立预测因素。使用经食管超声心动图早期检测LAA血栓可能有助于改善治疗策略并预防复发性脑卒中。
