Different Pb Generators and Its Radiation Safety Concerning Rn (Thoron) Emanation.

(1) Background: As the demand for Pb for clinical theranostics rises, empirical studies that examine the radiation safety implications of different Ra sources are needed to facilitate discussions with local authorities for the translation of Pb theranostics routine clinical practice. (2) Methods: Environmental Rn (Thoron) emanation was detected by a RAD7 detector in the vicinity of respective Pb sources and additional alpha-dosimeters to detect Rn during generator elution, radiosynthesis, and quality control. Personnel gamma exposure was measured using whole-body and ring dosimeters. Generators included those based on wet-chemical-process- and emanation-based technology. (3) Results: During generator handling, varying levels of Rn were observed in the vicinity of generators. An additional monthly whole-body dose must be considered when handling different sources of Pb generators, and this depends upon local shielding and the handling approaches toward use of the technology. (4) Conclusions: Ra in any form (including radionuclide generators) should always be handled within a fume hood to keep potential contamination and exposure to personnel as low as reasonably achievable. Following standard practices of radiation safety, generators of Pb can be used safely for theranostic applications.