一种用于迟发型超敏反应皮肤试验的新装置。

A new device for delayed hypersensitivity skin testing.

作者信息

Carle G, Duncan J L, Thomson S, Champagne C, Buchanan L, Keane M, Bistrian B R

出版信息

J Am Coll Nutr. 1985;4(5):515-20. doi: 10.1080/07315724.1985.10720093.

DOI:10.1080/07315724.1985.10720093

Abstract

A new device for assessment of delayed cutaneous hypersensitivity using seven standardized antigens (Multitest CMI) was compared to conventional intradermal testing with two recall antigens in 83 patients referred for nutritional support. Sixteen patients (19.3%) were anergic to Multitest CMI while four (4.8%) were anergic to conventional testing. Patients anergic to Multitest CMI had a higher complication (intraabdominal abscess, prolonged ileus, sepsis, pneumonia) than those who were immunocompetent by this test suggesting a group at greater risk. This interpretation is consistent with an increased specificity of Multitest CMI over conventional testing in the identification of clinically important anergy.

摘要

在83名因营养支持前来就诊的患者中，将一种使用七种标准化抗原的新型迟发性皮肤超敏反应评估装置（多重检测CMI）与使用两种回忆抗原的传统皮内试验进行了比较。16名患者（19.3%）对多重检测CMI无反应，而4名患者（4.8%）对传统检测无反应。对多重检测CMI无反应的患者比通过该检测免疫功能正常的患者有更高的并发症发生率（腹腔内脓肿、肠梗阻延长、败血症、肺炎），提示这是一个风险更高的群体。这一解释与多重检测CMI在识别临床上重要的无反应性方面比传统检测具有更高的特异性是一致的。