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经皮冷却射频消融胸段内侧支神经治疗慢性胸段疼痛

Cooled Radiofrequency Ablation of Thoracic Medial Branches for the Treatment of Chronic Thoracic Pain.

作者信息

Abd-Elsayed Alaa, Preda Alessandro, Shiferaw Barnabas T, Harrell Alexis K, Fiala Kenneth J

机构信息

Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, B6/319 CSC, Madison, WI 53792, USA.

Department of Natural Sciences and Mathematics, Spelman College, Atlanta, GA 30314, USA.

出版信息

Healthcare (Basel). 2025 Jun 18;13(12):1468. doi: 10.3390/healthcare13121468.

Abstract

Chronic thoracic pain is commonly caused by thoracic facet dysfunction, intercostal neuralgia, surgery, or thoracic pain secondary to cancer and is present in approximately 15% of the population. Conventional treatments, including pharmacotherapy and transcutaneous electrical nerve stimulation, are often ineffective and are often associated with poorly tolerated adverse effects. Cooled radiofrequency ablation (c-RFA) is a minimally invasive procedure that uses radiofrequency energy delivered through a probe to lesion the targeted nerve and provide significant and lasting relief. : This study was a retrospective analysis of data extracted from UW-Health Electronic Medical Health records from October 2015 through June 2024. Patient data were collected, including diagnosis, pre-operative pain score, post-operative pain score, duration of relief, age, sex, and BMI. A two-tailed paired -test was used to analyze the pre-operative and post-operative pain scores. A -value < 0.05 was considered significant. : A total of 111 thoracic c-RFA procedures were reviewed; 43 were excluded due to absent pre-operative or post-operative pain scores in medical records. A total of 68 procedures were included in the analysis, comprising 55 patients: 25 females and 30 males with an average age of 51.31 ± 18.22 years and a BMI of 29.79 ± 6.48 kg/m. Improvement in pain scores was reported in 77.94% (n = 53), 16.18% (n = 11) reported no change, and 5.88% (n = 4) reported worsening pain. Patients reported an average pre-operative pain score of 5.98 (M = 5.98, SD = 1.91) and an average post-operative pain score of 3.06 (M = 3.06, SD = 2.52); this achieved significance ( < 0.0001). Of the 77.94% (n = 53) charts that noted improvement, there is an average of 62.83 ± 28.48% reduction from their pre-operative pain scores. The average duration of relief lasted 11.85 ± 13.42 months. : This study supports the efficacy and safety of c-RFA as a minimally invasive therapy for chronic thoracic pain refractory to conservative measures.

摘要

慢性胸痛通常由胸段小关节功能障碍、肋间神经痛、手术或癌症继发的胸痛引起,约15%的人群存在该症状。包括药物治疗和经皮电刺激神经疗法在内的传统治疗方法往往无效,且常伴有耐受性差的不良反应。冷循环射频消融术(c-RFA)是一种微创手术,它利用通过探头传递的射频能量来损伤目标神经,从而提供显著且持久的缓解效果。本研究是一项回顾性分析,数据取自2015年10月至2024年6月的威斯康星大学健康电子病历。收集了患者数据,包括诊断、术前疼痛评分、术后疼痛评分、缓解持续时间、年龄、性别和体重指数。采用双尾配对t检验分析术前和术后疼痛评分。P值<0.05被认为具有统计学意义。共审查了111例胸段c-RFA手术;43例因病历中缺少术前或术后疼痛评分而被排除。分析共纳入68例手术,涉及55例患者:25名女性和30名男性,平均年龄为51.31±18.22岁,体重指数为29.79±6.48kg/m²。77.94%(n=53)的患者报告疼痛评分改善,16.18%(n=11)报告无变化,5.88%(n=4)报告疼痛加重。患者术前平均疼痛评分为5.98(M=5.98,SD=1.91),术后平均疼痛评分为3.06(M=3.06,SD=2.52);这具有统计学意义(P<0.0001)。在记录有改善的77.94%(n=53)的病例中,与术前疼痛评分相比平均降低了62.83±28.48%。缓解的平均持续时间为11.85±13.42个月。本研究支持c-RFA作为一种对保守治疗无效的慢性胸痛的微创治疗方法的有效性和安全性。

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