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前列腺切除术后盆底康复:基线严重程度作为改善的预测指标——一项前瞻性队列研究

Pelvic Floor Rehabilitation After Prostatectomy: Baseline Severity as a Predictor of Improvement-A Prospective Cohort Study.

作者信息

Terek-Derszniak Małgorzata, Biskup Małgorzata, Skowronek Tomasz, Nowak Mariusz, Falana Justyna, Jaskulski Jarosław, Obarzanowski Mateusz, Gozdz Stanislaw, Macek Pawel

机构信息

Holycross Cancer Centre, Department of Rehabilitation, Artwinskiego 3, 25-734 Kielce, Poland.

Collegium Medicum, Jan Kochanowski University of Kielce, Zeromskiego 5, 25-369 Kielce, Poland.

出版信息

J Clin Med. 2025 Jun 12;14(12):4180. doi: 10.3390/jcm14124180.

Abstract

: Urinary incontinence (UI) is a frequent and distressing complication after radical prostatectomy (RP). Pelvic floor muscle training (PFMT) is widely recommended as first-line rehabilitation, yet the clinical factors influencing its effectiveness remain incompletely understood. : This prospective cohort study included 182 men undergoing RP who completed a standardized physiotherapy program involving pelvic floor muscle exercises, biofeedback (BFB), and ultrasound-guided training. UI severity was assessed using the 1-h pad test and recorded absorbent product use. Outcomes were evaluated at three time points: one month, three months, and six months post-catheter removal. A multiple linear regression model was used to identify the predictors of continence improvement, defined as the change in pad test result between baseline and six months. : Pad test results and absorbent use decreased significantly across all UI severity stages ( < 0.0001). The greatest absolute improvement was observed in patients with severe incontinence at baseline (UI stage 3: mean reduction from 130.8 g to 23.7 g). Regression analysis revealed that only the baseline pad test result was significantly associated with the magnitude of improvement (β = 0.91; 95% CI: 0.85-0.97, < 0.001; R = 0.89). Age, BMI, and time to rehabilitation were not significant predictors. : Pelvic floor rehabilitation after RP is effective in improving continence, including in patients with severe baseline symptoms. The baseline pad test value emerged as the strongest predictor of rehabilitation response, highlighting the importance of initial assessment. These findings support the use of PFMT in clinical practice and emphasize the need for individualized treatment planning based on baseline UI severity.

摘要

尿失禁(UI)是根治性前列腺切除术(RP)后常见且令人苦恼的并发症。盆底肌训练(PFMT)被广泛推荐为一线康复治疗方法,但其有效性的临床影响因素仍未完全明确。

这项前瞻性队列研究纳入了182名接受RP手术的男性,他们完成了一项标准化的物理治疗方案,包括盆底肌锻炼、生物反馈(BFB)和超声引导训练。使用1小时尿垫试验评估尿失禁严重程度,并记录吸收性产品的使用情况。在拔除导尿管后的1个月、3个月和6个月这三个时间点评估结果。采用多元线性回归模型确定尿失禁改善的预测因素,定义为基线和6个月时尿垫试验结果的变化。

在所有尿失禁严重程度阶段,尿垫试验结果和吸收性产品的使用均显著下降(<0.0001)。基线时重度尿失禁患者(尿失禁3期:平均从130.8克降至23.7克)的绝对改善最大。回归分析显示,只有基线尿垫试验结果与改善幅度显著相关(β = 0.91;95%可信区间:0.85 - 0.97,<0.001;R = 0.89)。年龄、体重指数和康复时间不是显著的预测因素。

RP术后的盆底康复对改善尿失禁有效,包括基线症状严重的患者。基线尿垫试验值是康复反应的最强预测因素,突出了初始评估的重要性。这些发现支持在临床实践中使用PFMT,并强调需要根据基线尿失禁严重程度进行个体化治疗规划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/742a/12193967/21ab7226c765/jcm-14-04180-g001.jpg

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