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使用标准肾下分叉装置作为用于复杂腹主动脉瘤的四重开窗医生改良型内移植物——一项模拟研究

Using a Standard Infrarenal Bifurcated Device as a Quadruple-Fenestrated Physician-Modified Endograft for Complex Abdominal Aortic Aneurysms-A Simulation Study.

作者信息

Hüttl Artúr, Szentiványi András, Bérczi Ákos, Juhos Bendegúz, Szablics Fanni Éva, Osztrogonácz Péter, Csőre Judit, Borzsák Sarolta, Csobay-Novák Csaba

机构信息

Semmelweis Aortic Center, Department of Interventional Radiology, Heart and Vascular Center, Semmelweis University, Városmajor u. 68., H-1122 Budapest, Hungary.

Semmelweis Aortic Center, Department of Vascular and Endovascular Surgery, Heart and Vascular Center, Semmelweis University, Városmajor u. 68., H-1122 Budapest, Hungary.

出版信息

J Clin Med. 2025 Jun 15;14(12):4249. doi: 10.3390/jcm14124249.

DOI:10.3390/jcm14124249
PMID:40565994
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12194579/
Abstract

: We sought to demonstrate the versatility and economy of physician-modified endograft (PMEG) fenestrated endovascular aortic repair (FEVAR) based on the Treo (Terumo Aortic) platform for patients referred for custom-made device (CMD) FEVAR due to a complex abdominal aortic aneurysm (CAAA). Endovascular planning was performed utilizing a standardized design incorporating all visceral arteries with a low supra-celiac landing zone. The pure cost of the aortic components was compared between the PMEG and CMD designs. : A total of 39 consecutive patients treated with CMD FEVAR due to a CAAA between September 2018 and December 2023 were recruited at a tertiary vascular center for a retrospective evaluation. Endovascular planning was performed on readily available computed tomography angiography (CTA) datasets using 3Mensio Vascular (Pie Medical Imaging) software. The actual cost of the major components was compared between the implanted CMD platform produced by Cook and the planned Treo-based PMEG repair. : A total of 155 fenestrations were planned on 3 triple-, 34 quadruple-, and two quintuple-fenestrated devices. The 90 mm distance between the proximal edge and the flow divider of the 120 mm long main body of the Treo graft allowed for the placement of all necessary fenestrations of the target arteries without the need to reduce the 3 cm supra-celiac landing zone while also preserving a safety distance of >1 cm to the flow divider. The costs of the components were EUR 33896 for CMD and EUR 8878 for a PMEG. : This retrospective study suggests that a quadruple-fenestrated PMEG based on the Treo bifurcation is a highly versatile alternative with a significant price advantage over custom-made devices for the treatment of complex abdominal aortic aneurysms.

摘要

我们试图证明,对于因复杂腹主动脉瘤(CAAA)而转诊接受定制装置(CMD)开窗血管内主动脉修复术(FEVAR)的患者,基于Treo(泰尔茂主动脉)平台的医生改良型血管内移植物(PMEG)开窗血管内主动脉修复术具有多功能性和经济性。利用标准化设计进行血管内规划,该设计纳入了所有内脏动脉,并具有较低的膈上着陆区。比较了PMEG和CMD设计中主动脉组件的纯成本。

在一家三级血管中心招募了2018年9月至2023年12月期间因CAAA接受CMD FEVAR治疗的39例连续患者进行回顾性评估。使用3Mensio Vascular(Pie Medical Imaging)软件在现成的计算机断层扫描血管造影(CTA)数据集上进行血管内规划。比较了Cook生产的植入式CMD平台与计划的基于Treo的PMEG修复术之间主要组件的实际成本。

在3个三开窗、34个四开窗和2个五开窗装置上共规划了155个开窗。Treo移植物120 mm长主体的近端边缘与分流器之间90 mm的距离,使得能够放置目标动脉的所有必要开窗,而无需减小3 cm的膈上着陆区,同时还能保持与分流器>1 cm的安全距离。CMD组件成本为33896欧元,PMEG为8878欧元。

这项回顾性研究表明,基于Treo分叉的四开窗PMEG是一种高度通用的替代方案,在治疗复杂腹主动脉瘤方面比定制装置具有显著的价格优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fc8/12194579/ed83281cec8b/jcm-14-04249-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fc8/12194579/c0204d9fc164/jcm-14-04249-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fc8/12194579/ed83281cec8b/jcm-14-04249-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fc8/12194579/c0204d9fc164/jcm-14-04249-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fc8/12194579/ed83281cec8b/jcm-14-04249-g002.jpg

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本文引用的文献

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J Endovasc Ther. 2025 Feb 21:15266028251318952. doi: 10.1177/15266028251318952.
2
A standardized physician-modified endograft workflow utilizing the punch card technique and the Hungaroring reinforcement to treat complex abdominal aortic aneurysms.一种利用穿孔卡技术和匈牙利环增强技术治疗复杂腹主动脉瘤的标准化医生改良型腔内移植物工作流程。
J Vasc Surg Cases Innov Tech. 2024 Oct 22;11(1):101649. doi: 10.1016/j.jvscit.2024.101649. eCollection 2025 Feb.
3
Physician-Modified Endografts with the TREO Stent Graft System.
采用TREO支架移植物系统的医生改良型腔内移植物
J Endovasc Ther. 2024 Sep 26:15266028241282643. doi: 10.1177/15266028241282643.
4
Long-Term Results of Physician-Modified Endografts for the Treatment of Elective, Symptomatic, and Ruptured Juxtarenal Abdominal Aortic Aneurysms.择期、有症状和破裂的肾下腹部主动脉瘤的医师改良血管内移植物治疗的长期结果。
Ann Surg. 2024 Oct 1;280(4):633-639. doi: 10.1097/SLA.0000000000006422. Epub 2024 Jun 26.
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Fenestrated Endovascular Repair Using Short Tipped Distal Components with No Cross Concept to Prevent Crushing of Target Vessel Bridging Stents.使用无交叉概念的短尖端远端组件进行开窗血管内修复,以防止目标血管桥接支架受压。
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