Wang Kaitong, Zhang Huanhuan, Wei Han, Li Shigui, Zhang Ning, Si Huaijun
State Key Laboratory of Aridland Crop Science, Gansu Agricultural University, Lanzhou, China.
College of Agronomy, Gansu Agricultural University, Lanzhou, China.
Physiol Plant. 2025 Jul-Aug;177(4):e70357. doi: 10.1111/ppl.70357.
During plant evolution, several unique developmental processes have developed in response to growth and developmental needs. These processes may be related to the evolution of a family of plant-specific proteins, the Teosinte branched 1/Cycloidea/Proliferating cell factor (TCP) family, which originated in eukaryotes and has been expanding in plant evolution. In the last two decades, important breakthroughs have been made in the study of the biological functions of members of this family. Although all TCP proteins contain highly conserved DNA-binding domains, their biological functions are diverse. A large number of studies have shown that TCP transcription factors play regulatory roles by mediating complex signaling networks, which provide new perspectives for analyzing the regulatory mechanisms of plant development. In this review, the upstream regulatory networks, molecular components and target gene regulatory mechanisms of TCP transcription factors are discussed, and the core role of this protein family in plant growth and development is emphasized. In addition, we point out the insufficient integration and analysis in the current study, which will provide a theoretical basis for future multi-dimensional systematic research.
在植物进化过程中，为响应生长和发育需求，出现了几个独特的发育过程。这些过程可能与一类植物特有的蛋白质家族——玉米分枝1/环化蛋白/增殖细胞因子（TCP）家族的进化有关，该家族起源于真核生物，并在植物进化过程中不断扩展。在过去二十年里，该家族成员生物学功能的研究取得了重要突破。尽管所有TCP蛋白都含有高度保守的DNA结合结构域，但其生物学功能却多种多样。大量研究表明，TCP转录因子通过介导复杂的信号网络发挥调控作用，这为分析植物发育的调控机制提供了新视角。在这篇综述中，我们讨论了TCP转录因子的上游调控网络、分子组成部分和靶基因调控机制，并强调了该蛋白家族在植物生长发育中的核心作用。此外，我们指出了当前研究中整合与分析不足的问题，这将为未来的多维度系统研究提供理论依据。
