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每位重症监护医生都应了解的关于瑞马唑仑的知识。

What Every Intensivist Should Know About Remimazolam.

作者信息

Mathur Rhythm, Chittoria Konica, Sharma Ankur, Goyal Shilpa, Kothari Nikhil

机构信息

Department of Anaesthesiology and Critical Care, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Department of Trauma and Emergency (Anaesthesiology and Critical Care), All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

出版信息

Indian J Crit Care Med. 2025 Jun;29(6):531-533. doi: 10.5005/jp-journals-10071-24993. Epub 2025 Jun 5.

DOI:10.5005/jp-journals-10071-24993
PMID:40567326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12186073/
Abstract

UNLABELLED

Remimazolam, a recently developed benzodiazepine, possesses characteristics that make it an optimal sedative drug. These characteristics include a quicker onset, improved recovery, organ-independent metabolism, absence of accumulation, and rapid reversal with Flumazenil.

HOW TO CITE THIS ARTICLE

Mathur R, Chittoria K, Sharma A, Goyal S, Kothari N. What Every Intensivist Should Know About Remimazolam. Indian J Crit Care Med 2025;29(6):531-533.

摘要

未标注

瑞马唑仑是一种最近研发的苯二氮䓬类药物，具有使其成为理想镇静药物的特性。这些特性包括起效更快、恢复更佳、代谢不依赖器官、无蓄积以及使用氟马西尼可快速逆转。

如何引用本文

马图尔R、奇特托里亚K、夏尔马A、戈亚尔S、科塔里N。每位重症监护医生应了解的关于瑞马唑仑的知识。《印度重症监护医学杂志》2025年；29(6):531 - 533。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a27c/12186073/5e9f0ec89c66/ijccm-29-6-531-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a27c/12186073/5e9f0ec89c66/ijccm-29-6-531-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a27c/12186073/5e9f0ec89c66/ijccm-29-6-531-g001.jpg

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本文引用的文献

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Procedural sedative effect of remimazolam in ICU patients on invasive mechanical ventilation: a randomised, prospective study.瑞米唑仑对ICU有创机械通气患者的程序性镇静作用：一项随机、前瞻性研究。
Ann Intensive Care. 2025 Jan 14;15(1):8. doi: 10.1186/s13613-025-01431-5.
2
Association of remimazolam with delirium and cognitive function: A systematic review and meta-analysis of randomised controlled trials.瑞马唑仑与谵妄及认知功能的关联：一项随机对照试验的系统评价和荟萃分析
Eur J Anaesthesiol. 2025 Apr 1;42(4):285-297. doi: 10.1097/EJA.0000000000002107. Epub 2024 Dec 18.
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Comparison of the recovery time of remimazolam besylate and propofol for gastrointestinal endoscopy sedation in elderly patients.
比较苯磺酸雷米佐仑和丙泊酚用于老年患者胃肠镜检查镇静的恢复时间。
Int J Med Sci. 2024 May 13;21(7):1250-1256. doi: 10.7150/ijms.93045. eCollection 2024.
4
Remimazolam tosylate's long-term sedative properties in ICU patients on mechanical ventilation: effectiveness and safety.托西酸瑞马唑仑在机械通气 ICU 患者中的长期镇静特性：有效性和安全性。
Eur J Med Res. 2023 Oct 21;28(1):452. doi: 10.1186/s40001-023-01440-9.
5
Efficacy and safety of remimazolam-based sedation for intensive care unit patients undergoing upper gastrointestinal endoscopy: a cohort study.瑞马唑仑用于接受上消化道内镜检查的重症监护病房患者镇静的有效性和安全性：一项队列研究
World J Emerg Med. 2023;14(1):31-36. doi: 10.5847/wjem.j.1920-8642.2023.020.
6
Remimazolam: An Updated Review of a New Sedative and Anaesthetic.雷米唑仑：一种新型镇静和麻醉药物的更新综述。
Drug Des Devel Ther. 2022 Nov 15;16:3957-3974. doi: 10.2147/DDDT.S384155. eCollection 2022.
7
Remimazolam besylate for the sedation of postoperative patients undergoing invasive mechanical ventilation in the ICU: a prospective dose‒response study.苯磺酸瑞马唑仑用于 ICU 行有创机械通气术后患者镇静的前瞻性剂量反应研究。
Sci Rep. 2022 Nov 8;12(1):19022. doi: 10.1038/s41598-022-20946-6.
8
Remimazolam besylate versus propofol for long-term sedation during invasive mechanical ventilation: a pilot study.苯磺酸瑞马唑仑与丙泊酚用于有创机械通气患者长期镇静的比较：一项初步研究。
Crit Care. 2022 Sep 16;26(1):279. doi: 10.1186/s13054-022-04168-w.
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Efficacy and Safety of Remimazolam Besylate versus Dexmedetomidine for Sedation in Non-Intubated Older Patients with Agitated Delirium After Orthopedic Surgery: A Randomized Controlled Trial.甲磺酸瑞马唑仑与右美托咪定用于骨科手术后躁动谵妄非插管老年患者镇静的疗效和安全性：一项随机对照试验。
Drug Des Devel Ther. 2022 Aug 1;16:2439-2451. doi: 10.2147/DDDT.S373772. eCollection 2022.
10
Remimazolam versus traditional sedatives for procedural sedation: a systematic review and meta-analysis of efficacy and safety outcomes.瑞马唑仑与传统镇静剂用于镇静：疗效和安全性结局的系统评价和荟萃分析。
Minerva Anestesiol. 2022 Nov;88(11):939-949. doi: 10.23736/S0375-9393.22.16631-9. Epub 2022 Jul 5.