de Lacoste M C, Kirkpatrick J B, Ross E D
J Neuropathol Exp Neurol. 1985 Nov;44(6):578-91. doi: 10.1097/00005072-198511000-00004.
This study was undertaken to determine the topographical organization of fibers coursing through the human corpus callosum. We correlated the distribution of Wallerian degeneration in the corpus callosum with the anatomical sites of focal cortical lesions due to ischemic infarctions or circumscribed contusions. Fibers from the inferior frontal and anterior inferior parietal regions course through the rostrum and genu of the corpus callosum. Callosal connections from the temporo-parieto-occipital junctional region course through the splenium and caudal portion of the body of the corpus callosum. Both the superior parietal lobule and the occipital cortex give rise to interhemispheric fibers that course exclusively through the splenium of the corpus callosum. No callosal degeneration was associated with a cortical lesion in the anterior superior frontal region. The topographical organization of fibers in the human corpus callosum appears to be fairly similar to that found in the rhesus monkey (Macaca mulatta).
本研究旨在确定穿过人类胼胝体的纤维的拓扑组织。我们将胼胝体中沃勒变性的分布与缺血性梗死或局限性挫伤所致局灶性皮质病变的解剖部位进行了关联。来自额下回和顶下前区的纤维穿过胼胝体的嘴部和膝部。来自颞 - 顶 - 枕交界区的胼胝体连接纤维穿过胼胝体的压部和胼胝体体部的尾部。顶上小叶和枕叶皮质均发出仅穿过胼胝体压部的半球间纤维。额上前区的皮质病变未伴有胼胝体变性。人类胼胝体中纤维的拓扑组织似乎与恒河猴（猕猴）中发现的相当相似。
