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骨水泥强化椎弓根螺钉固定治疗转移性椎体压缩骨折患者后发生的肺水泥栓塞:一例报告及处理考量

Pulmonary cement embolism following cement-augmented pedicle screw fixation in a patient with metastatic vertebral compression fracture: A case report and management considerations.

作者信息

Daher Mohammad, Percheron Victor, Lampilas Adrien, Sebaaly Amer, Riouallon Guillaume, Bonhomme Stéphanie, Delrue Maxime

机构信息

Orthopedic Department, Hotel Dieu de France, Beirut, Lebanon.

Orthopedic Department, Brown University, Providence, RI.

出版信息

J Vasc Surg Cases Innov Tech. 2025 May 16;11(4):101845. doi: 10.1016/j.jvscit.2025.101845. eCollection 2025 Aug.

Abstract

We report the case of a 61-year-old female with metastatic rectal adenocarcinoma who underwent surgical fixation and laminectomy for an L3 vertebral compression fracture. Pedicle screws were augmented with cement. Follow-up computed tomography later detected an incidental pulmonary cement embolism in the right pulmonary artery. The patient remained asymptomatic and was managed with anticoagulation therapy. Subsequent gastrointestinal bleeding required temporary cessation of anticoagulation, but prophylactic anticoagulation was resumed due to the persistent embolus. At 6-month follow-up, the patient remained stable without hemorrhagic complications. In asymptomatic central pulmonary cement embolisms, anticoagulation may be appropriate but requires careful risk assessment and multidisciplinary management to balance the risks of thrombosis and bleeding.

摘要

我们报告了一例61岁患有转移性直肠腺癌的女性患者,该患者因L3椎体压缩性骨折接受了手术固定和椎板切除术。椎弓根螺钉用骨水泥强化。后续的计算机断层扫描后来在右肺动脉检测到一例偶然的肺部骨水泥栓塞。患者仍无症状,并接受了抗凝治疗。随后的胃肠道出血需要暂时停止抗凝,但由于栓塞持续存在,预防性抗凝治疗得以恢复。在6个月的随访中,患者保持稳定,无出血并发症。对于无症状的中央型肺部骨水泥栓塞,抗凝治疗可能是合适的,但需要仔细的风险评估和多学科管理,以平衡血栓形成和出血的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/848f/12191288/17fd3509a18d/gr1.jpg

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